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Target
Prostaglandin E2 receptor EP3 subtype
Ligand
BDBM212602
Substrate
n/a
Meas. Tech.
EP3 Radioligand SPA Binding Assay
pH
7.4±n/a
Temperature
298.15±n/a K
Ki
46±n/a nM
Comments
extracted
Citation
 Bahnck, KB; Edmonds, DJ; Futatsugi, K; Lee, EC; Mathiowetz, AM; Menhaji-Klotz, E; Stanton, RV Antagonists of prostaglandin EP3 receptor US Patent  US9278953 Publication Date 3/8/2016 
Target
Name:
Prostaglandin E2 receptor EP3 subtype
Synonyms:
PE2R3_HUMAN | PGE receptor, EP3 subtype | PGE2-R | PTGER3 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP3 subtype | Prostaglandin E2 receptor EP3 subtype (EP3) | Prostaglandin E2 receptor EP3A subtype (EP3A) | Prostaglandin E2 receptor EP3D subtype (EP3D) | Prostanoid EP3 receptor
Type:
Enzyme
Mol. Mass.:
43335.03
Organism:
Homo sapiens (Human)
Description:
P43115
Residue:
390
Sequence:
MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRYHTNNYASSSTSLPCQCSSTLMWSDHLER
  
Inhibitor
Name:
BDBM212602
Synonyms:
US9278953, 6
Type:
Small organic molecule
Emp. Form.:
C19H19N3O2
Mol. Mass.:
321.3731
SMILES:
Cn1ccc2cc(ccc12)-c1ccc(c(=O)[nH]1)[C@@]1(C)CCNC1=O |r|
Structure:
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