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Target
Alpha-amylase
Ligand
BDBM23406
Substrate
n/a
Meas. Tech.
Enzyme Activity Assay
pH
4.5±n/a
IC50
3.8e+3±n/a nM
Comments
extracted
Citation
 Pytelková, J; Lep?ík, M; Sanda, M; Talacko, P; Mare?ová, L; Mare?, M Enzymatic activity and immunoreactivity of Aca s 4, an alpha-amylase allergen from the storage mite Acarus siro. BMC Biochem 13:3 (2012) [PubMed]  Article 
Target
Name:
Alpha-amylase
Synonyms:
1,4-alpha-D-glucan glucanohydrolase | AMY_ACASI | Allergen: Aca s 4
Type:
Protein
Mol. Mass.:
58099.77
Organism:
Acarus siro (Flour mite)
Description:
B0KZK1
Residue:
517
Sequence:
MAHLLLAVVAITLALSQSVFGGSPYSNPHFTGSRSVITHLMQWKFDDIAAECERFLGPKGYGGIQLSPVNEHAVLGNRPWYELYQPVGYKIQSRSGNEEQFKGMVQRCNKVGVRIYVDIVMNHMSGAQEGHGNCWFKLQWHHDVSRCSLLVPNDFHGRESCHTDNMDIKNYDNPEEARNCRLSGLRDLKQSSEYVRQKQADFLNHLIDLGVAGSRSDASKHMWPGDLEAIYGKLHNLNTAYFPANSRPFIYHEVIYYGGDGIKSSDYTKLGRAIEFHFYRDIANVVRRHNQLKTVKNFGQPWGMVPSDDALVMVDSHDLQRFHTGQVGVNINYFESRLLKVATAFMLAWPYGVPRVMSSYHWDQKIEDGKDKNDWIGPPSDGSGNILSVTPQPDDTCNKEWICEHRWRQIYNMVHFRNVAGNEAVSHWWDNGDYQIAFGRGSKAFIAINLQDGQGLNRKLATGLPQGTYCDLVTGNLAGGKCTGGTVTVDGSGNADINIAKTAEDPFVAIHVEAKLH
  
Inhibitor
Name:
BDBM23406
Synonyms:
(3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}oxan-2-yl]oxy}-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-(hydroxymethyl)oxane-2,3,4-triol | Acarbose | US11292789, Acarbose
Type:
Carbohydrate
Emp. Form.:
C25H43NO18
Mol. Mass.:
645.6048
SMILES:
C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)OC(O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |t:37|
Structure:
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