Target
Tyrosine-protein kinase ABL2 [121-226]
Ligand
BDBM231647
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Assay
pH
7.25±n/a
Kd
2.6e+2± 7e+1 nM
Comments
extracted
Citation
 Gifford, SMLiu, WMader, CCHalo, TLMachida, KBoggon, TJKoleske, AJ Two amino acid residues confer different binding affinities of Abelson family kinase SRC homology 2 domains for phosphorylated cortactin. J Biol Chem 289:19704-13 (2014) [PubMed]  Article 
Target
Name:
Tyrosine-protein kinase ABL2 [121-226]
Synonyms:
ABL2 | ABL2_HUMAN | ABLL | ARG | Abelson tyrosine-kinase 2 SH2 domain (Arg SH2)
Type:
Protein
Mol. Mass.:
11881.50
Organism:
Homo sapiens (Human)
Description:
Truncated human Arg (121-226 aa)
Residue:
106
Sequence:
SGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTA
  
Inhibitor
Name:
BDBM231647
Synonyms:
SSPIpYEDAA | pY421
Type:
Small organic molecule
Emp. Form.:
C41H62N9O20P
Mol. Mass.:
1031.953
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(O)=O |r|
Structure:
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