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Target
Siderophore-binding protein
Ligand
BDBM50214744
Substrate
n/a
Meas. Tech.
CA Inhibition Assay
pH
7.5±n/a
Temperature
298.15±n/a K
Ki
3.6e+2±n/a nM
Comments
extracted
Citation
 Maresca, A; Vullo, D; Scozzafava, A; Manole, G; Supuran, CT Inhibition of the ß-class carbonic anhydrases from Mycobacterium tuberculosis with carboxylic acids. J Enzyme Inhib Med Chem 28:392-6 (2013) [PubMed]  Article 
Target
Name:
Siderophore-binding protein
Synonyms:
β-Carbonic anhydrase 3 (CA 3)
Type:
Enzyme
Mol. Mass.:
17663.22
Organism:
Mycobacterium tuberculosis
Description:
n/a
Residue:
174
Sequence:
MPLFSFEGRSPRIDPTAFVAPTATLIGDVTIEAGASVWFNAVLRGDYAPVVVREGANVQDGAVLHAPPGIPVDIGPGATVAHLCVIHGVHVGSEALIANHATVLDGAVIGARCMIAAGALVVAGTQIPAGMLVTGAPAKVKGPIEGTGAEMWVNVNPQAYRDLAARHLAGLEPM
  
Inhibitor
Name:
BDBM50214744
Synonyms:
(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid | (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid (10) | CHEMBL32749 | Ferulic acid (M5) | ferulic acid
Type:
Small organic molecule
Emp. Form.:
C10H10O4
Mol. Mass.:
194.184
SMILES:
COc1cc(\C=C\C(O)=O)ccc1O
Structure:
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