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Target
Beta-lactamase
Ligand
BDBM467001
Substrate
n/a
Meas. Tech.
Inhibition of Beta-Lactamase Enzymes
IC50
53.0±n/a nM
Citation
 Comita-Prevoir, J; Durand-Reville, TF; Gauthier, L; O''Donnell, J; Romero, J; Tommasi, R; Verheijen, JC; Wu, F; Wu, X; Zhang, J Beta-lactamase inhibitor compounds US Patent  US10800778 Publication Date 10/13/2020 
Target
Name:
Beta-lactamase
Synonyms:
Beta-lactamase | OXA-48 | Synonyms=blaOXA-48 | bla
Type:
PROTEIN
Mol. Mass.:
30363.94
Organism:
Klebsiella pneumoniae
Description:
ChEMBL_103606
Residue:
265
Sequence:
MRVLALSAVFLVASIIGMPAVAKEWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP
  
Inhibitor
Name:
BDBM467001
Synonyms:
2-(((2S,5R)-2-carbamoyl-4-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl)oxy)acetic acid lithium salt | US10800778, Example 93
Type:
Small organic molecule
Emp. Form.:
C10H13N3O5
Mol. Mass.:
255.2273
SMILES:
CC1=C[C@H](N2C[C@@H]1N(OCC(O)=O)C2=O)C(N)=O |r,t:1|
Structure:
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