Reaction Details Report a problem with these data
Target
Galectin-3
Ligand
BDBM468293
Substrate
n/a
Meas. Tech.
Evaluation of Kd Values
Kd
140±n/a nM
Citation
 Leffler, H; Nilsson, U; Zetterberg, F Hybrid galactoside inhibitor of galectins US Patent  US10800804 Publication Date 10/13/2020 
Target
Name:
Galectin-3
Synonyms:
LEG3_HUMAN | LGALS3 | MAC2
Type:
Enzyme
Mol. Mass.:
26156.54
Organism:
Homo sapiens (Human)
Description:
P17931
Residue:
250
Sequence:
MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
  
Inhibitor
Name:
BDBM468293
Synonyms:
US10800804, Example S20b
Type:
Small organic molecule
Emp. Form.:
C39H43FN4O9S
Mol. Mass.:
762.844
SMILES:
CC(C)(C)c1ccc2c(C(=O)NC3C(O)[C@@H](CO)OC(S[C@@H]4OC(CO)[C@H](O)[C@@H](C4O)n4cc(nn4)-c4cccc(F)c4)[C@@H]3O)c3ccccc3cc2c1 |r|
Structure:
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