Reaction Details Report a problem with these data
Target
HIV-1 protease
Ligand
BDBM468559
Substrate
n/a
Meas. Tech.
Enzyme Inhibition of Purified HIV-1 Protease
IC50
5.30±n/a nM
Citation
 Jude-Fishburn, CS; VanderVeen, LA; Riley, TA Protease inhibitors having enhanced features US Patent  US10806794 Publication Date 10/20/2020 
Target
Name:
HIV-1 protease
Synonyms:
HIV-1 protease wild type
Type:
Protein
Mol. Mass.:
10757.68
Organism:
Human immunodeficiency virus
Description:
O90785
Residue:
99
Sequence:
PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYEQVLIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF
  
Inhibitor
Name:
BDBM468559
Synonyms:
US10806794, Compound mPEG3-N-Darunavir
Type:
Small organic molecule
Emp. Form.:
C34H51N3O10S
Mol. Mass.:
693.848
SMILES:
COCCOCCOCCNc1ccc(cc1)S(=O)(=O)N(CC(C)C)CC(O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12 |r|
Structure:
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