Reaction Details Report a problem with these data
Target
HIV-1 protease
Ligand
BDBM468566
Substrate
n/a
Meas. Tech.
Enzyme Inhibition of Purified HIV-1 Protease
IC50
12.2±n/a nM
Citation
 Jude-Fishburn, CS; VanderVeen, LA; Riley, TA Protease inhibitors having enhanced features US Patent  US10806794 Publication Date 10/20/2020 
Target
Name:
HIV-1 protease
Synonyms:
HIV-1 protease wild type
Type:
Protein
Mol. Mass.:
10757.68
Organism:
Human immunodeficiency virus
Description:
O90785
Residue:
99
Sequence:
PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYEQVLIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF
  
Inhibitor
Name:
BDBM468566
Synonyms:
US10806794, Compound mPEG7-amide-Tipranavir
Type:
Small organic molecule
Emp. Form.:
C46H63F3N2O12S
Mol. Mass.:
925.059
SMILES:
CCC[C@@]1(CCc2ccccc2)CC(O)=C([C@H](CC)c2cccc(c2)N(CCOCCOCCOCCOCCOCCOCCOC)S(=O)(=O)c2ccc(cn2)C(F)(F)F)C(=O)O1 |t:15|
Structure:
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