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Target
Histone deacetylase 8
Ligand
BDBM163619
Substrate
n/a
Meas. Tech.
HDAC Inhibition
IC50
1500±n/a nM
Citation
 Liao, D; Roush, WR; Stowe, RL HDAC inhibitor compounds and methods of treatment US Patent  US10807944 Publication Date 10/20/2020 
Target
Name:
Histone deacetylase 8
Synonyms:
HD8 | HDAC8 | HDAC8_HUMAN | HDACL1 | Histone deacetylase 8 (HDAC-8) | Human HDAC8
Type:
Enzyme
Mol. Mass.:
41749.60
Organism:
Homo sapiens (Human)
Description:
Q9BY41
Residue:
377
Sequence:
MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
  
Inhibitor
Name:
BDBM163619
Synonyms:
UF010 | US10807944, Compound UF010 | US11731934, Compound UF010
Type:
Small organic molecule
Emp. Form.:
C11H15BrN2O
Mol. Mass.:
271.154
SMILES:
CCCCNNC(=O)c1ccc(Br)cc1
Structure:
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