Reaction Details Report a problem with these data
Target
Asialoglycoprotein receptor 1
Ligand
BDBM408863
Substrate
n/a
Meas. Tech.
SPR binding assay
Kd
1400±n/a nM
Citation
 Liras, S; Mascitti, V; Thuma, B Substituted-6,8-dioxabicyclo[3.2.1]octane-2,3-diol compounds as targeting agents of ASGPR US Patent  US10813942 Publication Date 10/27/2020 
Target
Name:
Asialoglycoprotein receptor 1
Synonyms:
ASGP-R 1 | ASGPR 1 | ASGR1 | ASGR1_HUMAN | CLEC4H1 | Hepatic lectin H1
Type:
PROTEIN
Mol. Mass.:
33177.60
Organism:
Homo sapiens (Human)
Description:
ChEMBL_603824
Residue:
291
Sequence:
MTKEYQDLQHLDNEESDHHQLRKGPPPPQPLLQRLCSGPRLLLLSLGLSLLLLVVVCVIGSQNSQLQEELRGLRETFSNFTASTEAQVKGLSTQGGNVGRKMKSLESQLEKQQKDLSEDHSSLLLHVKQFVSDLRSLSCQMAALQGNGSERTCCPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQHHIGPVNTWMGLHDQNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGGEDCAHFTDDGRWNDDVCQRPYRWVCETELDKASQEPPLL
  
Inhibitor
Name:
BDBM408863
Synonyms:
US10376531, Compound 24 | US10813942, Compound 24
Type:
Small organic molecule
Emp. Form.:
C9H12F3NO6
Mol. Mass.:
287.1899
SMILES:
OC[C@@]12CO[C@@H](O1)[C@H](NC(=O)C(F)(F)F)[C@@H](O)[C@H]2O |r|
Structure:
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