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Target
Mu-type opioid receptor
Ligand
BDBM472836
Substrate
n/a
Meas. Tech.
G-Protein Assay
EC50
10.00±n/a nM
Citation
 Tounge, BA; Bayoumy, S; Kuo, LC; Dax, SL Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same US Patent  US10836728 Publication Date 11/17/2020 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM472836
Synonyms:
3-[3-Dimethylaminomethyl-4-hydroxy-1-(3-phenyl-propyl)-piperidin-4-yl]-benzamide | US10836728, Compound (20)
Type:
Small organic molecule
Emp. Form.:
C24H31N3O
Mol. Mass.:
377.5224
SMILES:
CN(C)CC1CN(CCCc2ccccc2)CCC1(O)c1cccc(c1)C#N
Structure:
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