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Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM473002
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
1390±n/a nM
Citation
 Semple, G; Ren, AS; Schrader, TO; Kasem, M; Zhu, X 5-HT2C receptor agonists and compositions and methods of use US Patent  US10836764 Publication Date 11/17/2020 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A
Type:
undefined
Mol. Mass.:
52607.65
Organism:
Homo sapiens (Human)
Description:
P28223
Residue:
471
Sequence:
MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
  
Inhibitor
Name:
BDBM473002
Synonyms:
(R)-4-bromo-5,6,6a,7,8,9,10,11-octahydro- [1,4]diazepino[1,2-a][1,8]naphthyridine | US10836764, Compound 156
Type:
Small organic molecule
Emp. Form.:
C12H16BrN3
Mol. Mass.:
282.18
SMILES:
Brc1ccnc2N3CCCNC[C@H]3CCc12 |r|
Structure:
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