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Target
ADP-ribosylation factor 6
Ligand
BDBM475029
Substrate
n/a
Meas. Tech.
Biochemical Assay
IC50
5.50±n/a nM
Citation
 Ostanin, K; Shenderovich, M; Bajji, A; Cioffi, CL; Moss, N; Vankayalapati, H; Li, D Arf6 inhibitors and methods of synthesis and use thereof US Patent  US10849901 Publication Date 12/1/2020 
Target
Name:
ADP-ribosylation factor 6
Synonyms:
ARF6 | ARF6_HUMAN
Type:
Protein
Mol. Mass.:
20087.47
Organism:
Human
Description:
P62330
Residue:
175
Sequence:
MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS
  
Inhibitor
Name:
BDBM475029
Synonyms:
US10849901, Compound 79
Type:
Small organic molecule
Emp. Form.:
C22H15ClN4O
Mol. Mass.:
386.834
SMILES:
Clc1ccc(cc1)-c1c(nn2c1[nH]c(cc2=O)-c1cccc(c1)C#N)C1CC1
Structure:
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