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Target
ADP-ribosylation factor 6
Ligand
BDBM475063
Substrate
n/a
Meas. Tech.
Biochemical Assay
IC50
0.560±n/a nM
Citation
 Ostanin, K; Shenderovich, M; Bajji, A; Cioffi, CL; Moss, N; Vankayalapati, H; Li, D Arf6 inhibitors and methods of synthesis and use thereof US Patent  US10849901 Publication Date 12/1/2020 
Target
Name:
ADP-ribosylation factor 6
Synonyms:
ARF6 | ARF6_HUMAN
Type:
Protein
Mol. Mass.:
20087.47
Organism:
Human
Description:
P62330
Residue:
175
Sequence:
MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS
  
Inhibitor
Name:
BDBM475063
Synonyms:
US10849901, Compound 113
Type:
Small organic molecule
Emp. Form.:
C22H27N3O5S
Mol. Mass.:
445.532
SMILES:
CCC(C)(C)C1CCc2c(C1)sc1NC(NC(=O)c21)c1cc(OC)c(O)c(c1)[N+]([O-])=O
Structure:
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