Target
ADP-ribosylation factor 6
Ligand
BDBM475081
Substrate
n/a
Meas. Tech.
Biochemical Assay
IC50
11.0±n/a nM
Citation
 Ostanin, KShenderovich, MBajji, ACioffi, CLMoss, NVankayalapati, HLi, D Arf6 inhibitors and methods of synthesis and use thereof US Patent  US10849901 Publication Date 12/1/2020 
Target
Name:
ADP-ribosylation factor 6
Synonyms:
ARF6 | ARF6_HUMAN
Type:
Protein
Mol. Mass.:
20087.47
Organism:
Human
Description:
P62330
Residue:
175
Sequence:
MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS
  
Inhibitor
Name:
BDBM475081
Synonyms:
US10849901, Compound 131
Type:
Small organic molecule
Emp. Form.:
C15H14N4O2S
Mol. Mass.:
314.362
SMILES:
Cc1ccn2c(c1)nc(CSc1nc(C)cc(=O)[nH]1)cc2=O
Structure:
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