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Target
D(3) dopamine receptor
Ligand
BDBM476253
Substrate
n/a
Meas. Tech.
radioligand competition assay
Ki
0.780±0.2 nM
Citation
 Dutta, AK Neuroprotective agents for treatment of neurodegenerative diseases US Patent  US10874669 Publication Date 12/29/2020 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM476253
Synonyms:
(Z)-ethyl 5-(4-((tert-butyldimethylsilyl)oxy)-3-methoxyphenyl)pent-4-enoate | US10874669, Compound (-)-36 (D-601)
Type:
Small organic molecule
Emp. Form.:
C21H34O4Si
Mol. Mass.:
378.5778
SMILES:
CCOC(=O)CCC(=C)Cc1ccc(O[Si](C)(C)C(C)(C)C)c(OC)c1
Structure:
Search PDB for entries with ligand similarity: