Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM483467
Substrate
n/a
Meas. Tech.
Ligand-Displacement Binding
Ki
5269000±509000 nM
Citation
 Wainer, IW; Bernier, M; Toll, LR; Jimenez, LA Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas US Patent  US10925840 Publication Date 2/23/2021 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM483467
Synonyms:
US10925840, Compound (S,R)-2
Type:
Small organic molecule
Emp. Form.:
C19H24O4
Mol. Mass.:
316.3915
SMILES:
COc1ccc(C[C@@H](C)CC[C@@H](O)c2cc(O)cc(O)c2)cc1 |r|
Structure:
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