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Target
Beta-2 adrenergic receptor
Ligand
BDBM485865
Substrate
n/a
Meas. Tech.
cAMP Gs dynamic HTRF assay
EC50
>1000±n/a nM
Citation
 Ford, AP; Chen, W; Carter, DS; Yu, J Beta adrenergic agonist and methods of using the same US Patent  US10947196 Publication Date 3/16/2021 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM485865
Synonyms:
US10947196, Compound 03-1
Type:
Small organic molecule
Emp. Form.:
C12H17F3N2O
Mol. Mass.:
262.2714
SMILES:
CC(C)(C)NC[C@H](O)c1ncccc1C(F)(F)F |r|
Structure:
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