Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50370627
Substrate
n/a
Meas. Tech.
TBD
Ki
198±n/a nM
Citation
 Martin, SF; Sahn, JJ; Linkens, KT Sigma receptor binders US Patent  US10954217 Publication Date 3/23/2021 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Homo sapiens (Human)
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM50370627
Synonyms:
CHEMBL4169689 | US10954217, Example 00243
Type:
Small organic molecule
Emp. Form.:
C26H33N3O4
Mol. Mass.:
451.5579
SMILES:
CCOC(=O)CCN1CCN(CC1)c1ccc2CCN(Cc2c1)C(=O)OCc1ccccc1
Structure:
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