Assay Method Information

Assay Name:  Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain
Description:  Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assay Provider: James Granneman, Wayne State University Network: Molecular Library Probe Production Centers Network (MLPCN) Grant Proposal Number: 1 R21 NS061634-01 Grant Proposal PI: James Granneman, Wayne State University External Assay ID: ABHD5-MLDP_INH_LUMI_1536_3XIC50 2K Name: Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) (2K validation set). Description: Adipocytes are important regulators of vertebrate energy stores, in part through the storage of dietary fat (triglyceride) that is mobilized via lipolysis during fasting states for use by tissues such as heart and skeletal muscle (1, 2). However, in chronic conditions of overnutrition, such as obesity and lipid storage diso
Affinity data for this assay
 

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