| Assay Method Information | |
| | TR-FRET-based biochemical dose response competitive binding lanthascreen assay for partial agonists of the peroxisome proliferator-activated receptor gamma (PPARg) |
| Description: | Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TSRI Assay Provider: Patrick Griffin, TSRI Network: Molecular Library Probe Production Center Network (MLPCN) Grant Proposal Number: MH079861-01 Grant Proposal PI: Patrick Griffin, TSRI External Assay ID: PPARG_AG_TRFRET_0384_3XIC50 LANTHASCREEN DRUN Name: TR-FRET-based biochemical dose response competitive binding lanthascreen assay for partial agonists of the peroxisome proliferator-activated receptor gamma (PPARg). Description: Peroxisome proliferator-activated receptors (PPARs) belong to the nuclear receptor superfamily and are lipid sensors functioning as ligand-dependent transcription factors regulating gene expression patterns of diverse biological processes (1, 2). PPARs play a critical role in metabolic processes such as glucose metabolism, lipid metabolism, and have been implicated in anti-atherogenic, anti-inflammatory as well |
| Affinity data for this assay | |
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