| Assay Method Information | |
| | Counterscreen for agonists of the daf-12 abnormal Dauer Formation: Luminescence-based cell-based dose response assay to identify agonists of the Liver-X-Receptor (LXR). |
| Description: | Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf, UT Southwestern Network: Molecular Library Probe Production Centers Network (MLPCN) Grant Proposal Number: U19 DK062434 Grant Proposal Pi: David Mangelsdorf, UT Southwestern External Assay ID: LXR_ACT_LUMI_1536_3XEC50 DCSRUN Name: Counterscreen for agonists of the daf-12 abnormal Dauer Formation: Luminescence-based cell-based dose response assay to identify agonists of the Liver-X-Receptor (LXR). Description: Parasitic helminthes (worms) are a significant health and economic burden: over two billion people are infected by helminthes [1], and parasitic nematodes cause billions of dollars of crop damage each year in the United States [2]. The developmental stages of these organisms are widely studied [3, 4]. One stage, dauer (German for "duration", also known as an alternative L3 larval stage) covers an alternative larval stage in which |
| Affinity data for this assay | |
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