BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,346K data for 622K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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22 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis of halogenated trimetoquinol derivatives and evaluation of their beta-agonist and thromboxane A2 (TXA2) antagonist activities.EBI
Ohio State University
Synthesis and structure-activity relationships of long-acting beta2 adrenergic receptor agonists incorporating arylsulfonamide groups.EBI
Glaxosmithkline
The 3,4-catechol derivative of propranolol, a minor dihydroxylated metabolite.EBI
TBA
Synthesis and beta-adrenergic blocking activity of new aliphatic and alicyclic oxime ethers.EBI
TBA
Beta 1-selective adrenoceptor antagonists: examples of the 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazole class.EBI
TBA
Ultra-short-acting beta-adrenergic receptor blocking agents. 2. (Aryloxy)propanolamines containing esters on the aryl function.EBI
TBA
Ultra-short-acting beta-adrenergic receptor blocking agents. 1. (Aryloxy)propanolamines containing esters in the nitrogen substituent.EBI
TBA
2-Benzodioxinylaminoethanols: a new class of beta-adrenergic blocking and antihypertensive agents.EBI
TBA
Synthesis and beta-adrenergic blocking activity of new aliphatic oxime ethers.EBI
TBA
Alpha- and beta-adrenoceptors: from the gene to the clinic. 2. Structure-activity relationships and therapeutic applications.EBI
Smithkline Beecham Pharmaceuticals
Conformationally restrained analogs of sympathomimetic catecholamines. Synthesis, conformational analysis, and adrenergic activity of isochroman derivatives.EBI
Universit£
Synthesis and hypoglycemic activity of substituted 8-(1-piperazinyl)imidazo[1,2-a]pyrazines.EBI
Merck Sharp And Dohme Research Laboratories
Syntheses and adrenergic activities of ring-fluorinated epinephrines.EBI
National Institute Of Diabetes
 
SYNTHESIS AND BIOLOGICAL EVALUATION OF A FLUORINATED ANALOG OF THE β-ADRENERGIC BLOCKING AGENT, METOPROLOLEBI
TBA
 
Asymmetric synthesis of FR165914: A novel β3-adrenergic agonist with a benzocycloheptene structureEBI
TBA
The [(methyloxy)imino]methyl moiety as a bioisoster of aryl. A novel class of completely aliphatic beta-adrenergic receptor antagonists.EBI
Universitá
A new series of tricyclic (aryloximino)propanolamines displaying very high selective beta 2-blocking properties.EBI
Université
Effect of fluorine substitution on the adrenergic properties of 3-(tert-butylamino)-1-(3,4-dihydroxyphenoxy)-2-propanol.EBI
National Institute Of Diabetes
RS-102221: a novel high affinity and selective, 5-HT2C receptor antagonist.BDB
Roche Bioscience
BW 723C86, a 5-HT2B receptor agonist, causes hyperphagia and reduced grooming in rats.BDB
Smithkline Beecham Pharmaceuticals
Novel discriminatory ligands for 5-HT2B receptors.BDB
Smithkline Beecham Pharmaceuticals
Biochemical and pharmacological characterization of high-affinity trimetoquinol analogs on guinea pig and human beta adrenergic receptor subtypes: evidence for partial agonism.BDB
Ohio State University