PMID

Data

Article Title

Organization

Rapid preparation of (3R,4S,5R) polyhydroxylated pyrrolidine-based libraries to discover a pharmacological chaperone for treatment of Fabry disease.

National Cheng Kung University

Bioevaluation of sixteen ADMDP stereoisomers toward alpha-galactosidase A: Development of a new pharmacological chaperone for the treatment of Fabry disease and potential enhancement of enzyme replacement therapy efficiency.

National Cheng Kung University

Synthesis of C-5a-chain extended derivatives of 4-epi-isofagomine: Powerfulß-galactosidase inhibitors and low concentration activators of GM1-gangliosidosis-related human lysosomalß-galactosidase.

Graz University Of Technology

Biological properties of D- and L-1-deoxyazasugars.

Toyama Medical And Pharmaceutical University

Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases.

Hokuriku University

2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease.

University Of Toyama

 

Synthesis of a new inhibitor of α-fucosidase

TBA

 

Synthesis of C₂-symmetrical polyhydroxyazepanes as inhibitors of glycosidases

TBA

Novel O-glycosyl amino acid mimetics as building blocks for O-glycopeptides act as inhibitors of galactosidases.

University Of Hamburg

Specific, uncompetitive inhibition of beta-galactosidases by a 5,6-isopropylidenedioxyfuro[2,3-d]isoxazole-3-methanol derivative.

Institut De Chimie Organique De L'Université

Tuning of ?-glucosidase and ?-galactosidase inhibition by generation and in situ screening of a library of pyrrolidine-triazole hybrid molecules.

University Of Seville

Synthesis of (3S,4S,5S)-trihydroxylpiperidine derivatives as enzyme stabilizers to improve therapeutic enzyme activity in Fabry patient cell lines.

National Yang-Ming University