The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,346K data for 622K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Advanced Search

21 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis, experimental evaluation and molecular modelling of hydroxamate derivatives as zinc metalloproteinase inhibitors.EBI
Uit The Arctic University Of Norway
Additivity or cooperativity: which model can predict the influence of simultaneous incorporation of two or more functionalities in a ligand molecule?EBI
The State University Of New York
Synthesis and enzymatic evaluation of phosphoramidon and itsß anomer: Anomerization ofa-l-rhamnose triacetate upon phosphitylation.EBI
Jiangxi Science And Technology Normal University
Water mediated ligand functional group cooperativity: the contribution of a methyl group to binding affinity is enhanced by a COO(-) group through changes in the structure and thermodynamics of the hydration waters of ligand-thermolysin complexes.EBI
The State University Of New York
Hydroxamic acids as potent inhibitors of endothelin-converting enzyme from human bronchiolar smooth muscle.EBI
Berlex Laboratories
New thiol inhibitors of neutral endopeptidase EC 3.4.24.11: synthesis and enzyme active-site recognition.EBI
University Of Paris
Excursions in drug discovery.EBI
Merck Research Laboratories
Definition and display of steric, hydrophobic, and hydrogen-bonding properties of ligand binding sites in proteins using Lee and Richards accessible surface: validation of a high-resolution graphical tool for drug design.EBI
Ciba-Geigy
Silanediol-based inhibitor of thermolysin.EBI
State University Of New York
 
Thiol and hydroxamic acid containing inhibitors of endothelin converting enzymeEBI
TBA
Identification of novel quinazolin-4(3H)-ones as inhibitors of thermolysin, the prototype of the M4 family of proteinases.EBI
University Of Troms£
 
Inhibitory stereochemistry of N-chloroacetyl-N-hydroxyleucine methyl ester for thermolysinEBI
TBA
Discovery of potent thermolysin inhibitors using structure based virtual screening and binding assays.EBI
University Of Tromsø
Reversed hydroxamate-bearing thermolysin inhibitors mimic a high-energy intermediate along the enzyme-catalyzed proteolytic reaction pathway.EBI
Pohang University Of Science And Technology
Inhibition stereochemistry of hydroxamate inhibitors for thermolysin.EBI
Pohang University Of Science And Technology
Inhibition of thermolysin with nitrone-bearing substrate analogs: a new type of thermolysin inhibitors.EBI
Pohang University Of Science And Technology
Meta-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors.EBI
Ciba-Geigy
Ortho-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors.EBI
Novartis Pharmaceuticals
Biological activity of tropolone.EBI
Osaka Organic Chemical Industry
Development of new hydrogen-bond descriptors and their application to comparative molecular field analyses.EBI
University Of Marburg
SMall Molecule Growth 2001 (SMoG2001): an improved knowledge-based scoring function for protein-ligand interactions.EBI
Harvard University