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22 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis and evaluation of the antiparasitic activity of bis-(arylmethylidene) cycloalkanones.EBI
Universidade Federal De Minas Gerais
Design, synthesis and biological evaluation of novel nitroaromatic compounds as potent glutathione reductase inhibitors.EBI
Batman University
In vitro inhibition of human erythrocyte glutathione reductase by some new organic nitrates.EBI
Atat£Rk University
High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity.EBI
Harvard Medical School
Inhibitors of Trypanosoma cruzi trypanothione reductase revealed by virtual screening and parallel synthesis.EBI
Universit£T Heidelberg
Use of an additional hydrophobic binding site, the Z site, in the rational drug design of a new class of stronger trypanothione reductase inhibitor, quaternary alkylammonium phenothiazines.EBI
University Of Manchester
Synthesis, activity, and molecular modeling of a new series of tricyclic pyridazinones as selective aldose reductase inhibitors.EBI
TBA
Optimising inhibitors of trypanothione reductase using solid-phase chemistry.EBI
University Of Southamton
Dihydroquinazolines as a novel class of Trypanosoma brucei trypanothione reductase inhibitors: discovery, synthesis, and characterization of their binding mode by protein crystallography.EBI
University Of Dundee
Compounds structurally related to ellagic acid show improved antiplasmodial activity.EBI
Justus-Liebig-University
Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis.EBI
National Human Genome Research Institute
Interactions of methylene blue with human disulfide reductases and their orthologues from Plasmodium falciparum.EBI
Biochemie-Zentrum Der Universit£T Heidelberg
Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening.EBI
Institute Of Medical Research
Novel alkylpolyaminoguanidines and alkylpolyaminobiguanides with potent antitrypanosomal activity.EBI
Wayne State University
Irreversible inactivation of trypanothione reductase by unsaturated Mannich bases: a divinyl ketone as key intermediate.EBI
Biochemie-Zentrum Der UniversitäT Heidelberg
Synthesis of 5-nitro-2-furancarbohydrazides and their cis-diamminedichloroplatinum complexes as bitopic and irreversible human thioredoxin reductase inhibitors.EBI
Umr 8525 Cnrs-Université
5-substituted tetrazoles as bioisosteres of carboxylic acids. Bioisosterism and mechanistic studies on glutathione reductase inhibitors as antimalarials.EBI
Université
A prodrug form of a Plasmodium falciparum glutathione reductase inhibitor conjugated with a 4-anilinoquinoline.EBI
Umr 8525 Cnrs-Université
Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine.EBI
University Of Cape Town
Inhibition of human glutathione reductase by 10-arylisoalloxazines: crystalline, kinetic, and electrochemical studies.EBI
Institut FüR Biochemie Ii Der UniversitäT