22 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Synthesis and evaluation of the antiparasitic activity of bis-(arylmethylidene) cycloalkanones.
Universidade Federal De Minas Gerais
Design, synthesis and biological evaluation of novel nitroaromatic compounds as potent glutathione reductase inhibitors.
Batman University
In vitro inhibition of human erythrocyte glutathione reductase by some new organic nitrates.
Atat£Rk University
High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity.
Harvard Medical School
Inhibitors of Trypanosoma cruzi trypanothione reductase revealed by virtual screening and parallel synthesis.
Universit£T Heidelberg
Use of an additional hydrophobic binding site, the Z site, in the rational drug design of a new class of stronger trypanothione reductase inhibitor, quaternary alkylammonium phenothiazines.
University Of Manchester
Synthesis, activity, and molecular modeling of a new series of tricyclic pyridazinones as selective aldose reductase inhibitors.
TBA
Optimising inhibitors of trypanothione reductase using solid-phase chemistry.
University Of Southamton
Dihydroquinazolines as a novel class of Trypanosoma brucei trypanothione reductase inhibitors: discovery, synthesis, and characterization of their binding mode by protein crystallography.
University Of Dundee
Compounds structurally related to ellagic acid show improved antiplasmodial activity.
Justus-Liebig-University
Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis.
National Human Genome Research Institute
Interactions of methylene blue with human disulfide reductases and their orthologues from Plasmodium falciparum.
Biochemie-Zentrum Der Universit£T Heidelberg
Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening.
Institute Of Medical Research
Novel alkylpolyaminoguanidines and alkylpolyaminobiguanides with potent antitrypanosomal activity.
Wayne State University
Irreversible inactivation of trypanothione reductase by unsaturated Mannich bases: a divinyl ketone as key intermediate.
Biochemie-Zentrum Der UniversitäT Heidelberg
Synthesis of 5-nitro-2-furancarbohydrazides and their cis-diamminedichloroplatinum complexes as bitopic and irreversible human thioredoxin reductase inhibitors.
Umr 8525 Cnrs-Université
5-substituted tetrazoles as bioisosteres of carboxylic acids. Bioisosterism and mechanistic studies on glutathione reductase inhibitors as antimalarials.
Université
A prodrug form of a Plasmodium falciparum glutathione reductase inhibitor conjugated with a 4-anilinoquinoline.
Umr 8525 Cnrs-Université
Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine.
University Of Cape Town