102 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
New quinolinic derivatives as melatonergic ligands: Synthesis and pharmacological evaluation.
Universities of Lille
2-Amido-8-methoxytetralins: a series of nonindolic melatonin-like agents.
University of Groningen
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
Jagiellonian University Medical College
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
Jagiellonian University Medical College
Tactical Approaches to Interconverting GPCR Agonists and Antagonists.
University of Minnesota
Melatonergic ligands: Design, synthesis and pharmacological evaluation of novel series of naphthofuranic derivatives.
University of Lille
Synthesis of 2-arylfuro[3,2-b]pyridines: Effect of the C2-aryl group on melatoninergic activity.
Orleans University
New coumarin-based fluorescent melatonin ligands. Design, synthesis and pharmacological characterization.
IQM-CSIC
Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines.
University of Urbino
Novel N-Acetyl Bioisosteres of Melatonin: Melatonergic Receptor Pharmacology, Physicochemical Studies, and Phenotypic Assessment of Their Neurogenic Potential.
IQM-CSIC
Efficient synthesis of hexahydroindenopyridines and their potential as melatoninergic ligands.
Universidad De Valencia
MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential.
The German University In Cairo
Development of substituted N-[3-(3-methoxylphenyl)propyl] amides as MT(2)-selective melatonin agonists: improving metabolic stability.
Hong Kong University of Science and Technology
Synthesis of new N-(arylcyclopropyl)acetamides and N-(arylvinyl)acetamides as conformationally-restricted ligands for melatonin receptors.
Paris-Sud University
Bivalent ligand approach on N-{2-[(3-methoxyphenyl)methylamino]ethyl}acetamide: synthesis, binding affinity and intrinsic activity for MT(1) and MT(2) melatonin receptors.
University of Urbino
Design, synthesis, and pharmacological effects of structurally simple ligands for MT(1) and MT(2) melatonin receptors.
University of Bari Aldo Moro
Pharmacophoric search and 3D-QSAR comparative molecular field analysis studies on agonists of melatonin sheep receptors.
Orleans University
4-(1-Phenyl-1H-pyrazol-4-yl)quinolines as novel, selective and brain penetrant metabotropic glutamate receptor 4 positive allosteric modulators.
Lundbeck Research Usa
Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.
University of Namur
Discovery of N-{1-[3-(3-oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): an allosteric muscarinic M1 receptor agonist with unprecedented selectivity and procognitive potential.
H. Lundbeck
Design, synthesis and pharmacological evaluation of novel naphthalenic derivatives as selective MT(1) melatoninergic ligands.
University of Lille
Mapping the melatonin receptor. 6. Melatonin agonists and antagonists derived from 6H-isoindolo[2,1-a]indoles, 5,6-dihydroindolo[2,1-a]isoquinolines, and 6,7-dihydro-5H-benzo[c]azepino[2,1-a]indoles.
King'S College London
Design and synthesis of 2-phenylimidazo[1,2-a]pyridines as a novel class of melatonin receptor ligands.
Orleans University
Synthesis of a novel series of tricyclic dihydrofuran derivatives: discovery of 8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridines as melatonin receptor (MT1/MT2) ligands.
Takeda Pharmaceutical
Preparation and pharmacological evaluation of a novel series of 2-(phenylthio)benzo[b]thiophenes as selective MT2 receptor ligands.
University of Lille
1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT2-selective agonists.
Takeda Pharmaceutical
Design and synthesis of naphthalenic derivatives as new ligands at the melatonin binding site MT3.
University of Lille
Design and synthesis of 1-(2-alkanamidoethyl)-6-methoxy-7-azaindole derivatives as potent melatonin agonists.
Orleans University
A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.
Università
Synthesis of substituted N-[3-(3-methoxyphenyl)propyl] amides as highly potent MT(2)-selective melatonin ligands.
Hong Kong University of Science and Technology
Synthesis and pharmacological evaluation of 1,2,3,4-tetrahydropyrazino[1,2-a]indole and 2-[(phenylmethylamino)methyl]-1H-indole analogues as novel melatoninergic ligands.
University of W£Rzburg
Synthesis and receptor binding studies of quinolinic derivatives as melatonin receptor ligands
TBA
2-[(2,3-dihydro-1H-indol-1-yl)methyl]melatonin analogues: a novel class of MT2-selective melatonin receptor antagonists.
University of WüRzburg
Synthesis of 3-phenylnaphthalenic derivatives as new selective MT(2) melatoninergic ligands.
University of Lille 2
Synthesis and pharmacological evaluation of pentacyclic 6a,7-dihydrodiindole and 2,3-dihydrodiindole derivatives as novel melatoninergic ligands.
University of WüRzburg
Design and synthesis of benzofuranic derivatives as new ligands at the melatonin-binding site MT3.
Université
The location, physiology, pathology of hippocampus Melatonin MT2 receptor and MT2-selective modulators.
The First Affiliated Hospital of China Medical University
2-Arylmelatonin analogues: Probing the 2-phenyl binding pocket of melatonin MT
University of Urbino Carlo Bo
Natural spirocyclic alkaloids and polyphenols as multi target dementia leads.
Rmit University
Recent research progress of Uncaria spp. based on alkaloids: phytochemistry, pharmacology and structural chemistry.
China Pharmaceutical University
Mapping the melatonin receptor. 7. Subtype selective ligands based on beta-substituted N-acyl-5-methoxytryptamines and beta-substituted N-acyl-5-methoxy-1-methyltryptamines.
University of Athens
The Repertoire of Small-Molecule PET Probes for Neuroinflammation Imaging: Challenges and Opportunities beyond TSPO.
Massachusetts General Hospital
Design and Validation of the First Family of Photo-Activatable Ligands for Melatonin Receptors.
University of Paris
Synthesis and biological evaluation of paeoveitol D derivatives as new melatonin receptor agonists with antidepressant activities.
Chinese Academy of Sciences
(R)-2-(4-Phenylbutyl)dihydrobenzofuran derivatives as melatoninergic agents.
Bristol-Myers Squibb Pharmaceutical Research Institute
Tetrahydroisoquinoline derivatives as melatonin MT2 receptor antagonists.
Bristol-Myers Squibb Pharmaceutical Research Institute
N-[2-[2-(4-Phenylbutyl)benzofuran-4-yl]cyclopropylmethyl]acetamide: an orally bioavailable melatonin receptor agonist.
Bristol-Myers Squibb Pharmaceutical Research Institute
Synthesis and structure-activity relationship of novel benzoxazole derivatives as melatonin receptor agonists.
Bristol-Myers Squibb Pharmaceutical Research Institute
4-Substituted anilides as selective melatonin MT2 receptor agonists.
Bristol-Myers Squibb Pharmaceutical Research Institute
Discovery of a Potent and Orally Bioavailable Melatonin Receptor Agonist.
Takeda Pharmaceutical
Design and synthesis of benzoxazole derivatives as novel melatoninergic ligands.
Bristol-Myers Squibb Pharmaceutical Research Institute
Heterocyclic aminopyrrolidine derivatives as melatoninergic agents.
Bristol-Myers Squibb Pharmaceutical Research Institute
Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties.
IQM-CSIC
Design and synthesis of naphthalenic dimers as selective MT1 melatoninergic ligands.
Université
Indanyl piperazines as melatonergic MT2 selective agents.
Bristol-Myers Squibb Pharmaceutical Research Institute
Synthesis of a novel series of tricyclic indan derivatives as melatonin receptor agonists.
Takeda Chemical Industries
Synthesis of a novel series of benzocycloalkene derivatives as melatonin receptor agonists.
Takeda Chemical Industries
Synthesis and structure-affinity-activity relationships of novel benzofuran derivatives as MT(2) melatonin receptor selective ligands.
Institut De Chimie Pharmaceutique Albert Lespagnol
Synthesis of nitroindole derivatives with high affinity and selectivity for melatoninergic binding sites MT(3).
Institut De Chimie Pharmaceutique Albert Lespagnol
Quinazoline and phthalazine derivatives as novel melatonin receptor ligands analogues of agomelatine.
Umr-S1172 - Jparc - Centre De Recherche Jean-Pierre Aubert Neurosciences Et Cancer
Synthesis of phenalene and acenaphthene derivatives as new conformationally restricted ligands for melatonin receptors.
Paris-Sud University
Design, Synthesis, and Characterization of Ogerin-Based Positive Allosteric Modulators for G Protein-Coupled Receptor 68 (GPR68).
Icahn School Of Medicine At Mount Sinai
Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships.
Chinese Academy of Sciences
Development of a high-affinity ligand that binds irreversibly to Mel1b melatonin receptors.
Duquesne University
Indole-based melatonin analogues: Synthetic approaches and biological activity.
Nantong University
Original Design of Fluorescent Ligands by Fusing BODIPY and Melatonin Neurohormone.
Orleans University
N-(substituted-anilinoethyl)amides: design, synthesis, and pharmacological characterization of a new class of melatonin receptor ligands.
University of Parma
7-Substituted-melatonin and 7-substituted-1-methylmelatonin analogues: effect of substituents on potency and binding affinity.
University College London
Analysis of structure-activity relationships for MT2 selective antagonists by melatonin MT1 and MT2 receptor models.
University of Parma
Tricyclic alkylamides as melatonin receptor ligands with antagonist or inverse agonist activity.
University of Milan
Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation.
University of Parma
2-N-acylaminoalkylindoles: design and quantitative structure-activity relationship studies leading to MT2-selective melatonin antagonists.
University of Urbino
Melatonin receptor ligands: synthesis of new melatonin derivatives and comprehensive comparative molecular field analysis (CoMFA) study.
University of Milan
1-(2-Alkanamidoethyl)-6-methoxyindole derivatives: a new class of potent indole melatonin analogues.
University of Urbino
Conformationally restrained melatonin analogues: synthesis, binding affinity for the melatonin receptor, evaluation of the biological activity, and molecular modeling study.
University of Urbino
Synthesis and structure-activity relationships of novel naphthalenic and bioisosteric related amidic derivatives as melatonin receptor ligands.
Institut De Chimie Pharmaceutique
2-Substituted 5-methoxy-N-acyltryptamines: synthesis, binding affinity for the melatonin receptor, and evaluation of the biological activity.
University of Urbino
Synthesis and biological evaluation of magnolol derivatives as melatonergic receptor agonists with potential use in depression.
Chinese Academy of Sciences
Synthesis and biological evaluation of new naphtho- and quinolinocyclopentane derivatives as potent melatoninergic (MT
Univ. Lille
Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit.
University of Urbino
Oxyprenylated Phenylpropanoids Bind to MT1 Melatonin Receptors and Inhibit Breast Cancer Cell Proliferation and Migration.
Duquesne University
Identification and biological evaluation of thiazole-based inverse agonists of RORĪ³t.
Phenex Pharmaceuticals
Tetrahydroquinoline Ring as a Versatile Bioisostere of Tetralin for Melatonin Receptor Ligands.
University of Parma
N-(2-(substituted-naphth-1-yl)ethyl) substituted amide compound, preparation and uses thereof
Beijing Greatway Pharmaceutical Technology Co.
Compounds, process for obtaining the compounds, pharmaceutical composition, use of the compounds and method for treating psychiatric disorders and/or sleep disorders
AchÉ
Compounds, process for obtaining the compounds, pharmaceutical composition, use of the compounds and method for treating psychiatric disorders and/or sleep disorders
AchÉ
SR147778 [5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a new potent and selective antagonist of the CB1 cannabinoid receptor: biochemical and pharmacological characterization.
Sanofi-Synthelabo Recherche
Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder.
Eli Lilly
Comparison of the structure-activity relationships of melatonin receptor agonists and antagonists: lengthening the N-acyl side-chain has differing effects on potency on Xenopus melanophores.
King'S College London
2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists.
Universita Degli Studi Di Milano
Pharmacological characterization of the human melatonin Mel1a receptor following stable transfection into NIH3T3 cells.
Universit&Aagrove
GR196429: a nonindolic agonist at high-affinity melatonin receptors.
Glaxo Wellcome Research and Development
Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor.
Northwestern University