21 articles for J Kallen
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors.
Novartis Institutes For Biomedical Research
Tetra-substituted imidazoles as a new class of inhibitors of the p53-MDM2 interaction.
Novartis Institutes For Biomedical Research
The central valine concept provides an entry in a new class of non peptide inhibitors of the p53-MDM2 interaction.
Novartis Institutes For Biomedical Research
1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1.
Novartis Institutes For Biomedical Research
Oxamyl dipeptide caspase inhibitors developed for the treatment of stroke.
Idun Pharmaceuticals
Structure-based design of potent linear peptide inhibitors of the YAP-TEAD protein-protein interaction derived from the YAP omega-loop sequence.
Novartis Institutes For Biomedical Research
Rational design, synthesis, and X-ray structure of selective noncovalent thrombin inhibitors.
Novartis Pharma
In vitro and in vivo characterization of a novel, highly potent p53-MDM2 inhibitor.
Novartis Institutes For Biomedical Research
Optimizing a Weakly Binding Fragment into a Potent RORĪ³t Inverse Agonist with Efficacy in an in Vivo Inflammation Model.
TBA
Process route of compound of formula (IV), crystal form and preparation method therefor
Shandong Danhong Pharmaceutical Co.
1-cyclohexyl-2-phenylaminobenzimidazoles as mIDH1 inhibitors for the treatment of tumors
Bayer Pharma Aktiengesellschaft
Substituted pyrimido[1,2-b]indazoles and their use as modulators of the Pi3K/Akt pathway
Bayer Intellectual Property
A facile one-pot synthesis of 2-arylamino-5-aryloxylalkyl-1,3,4-oxadiazoles and their urease inhibition studies.
Mirpur University of Science and Technology (Must)
Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b).
Roche Bioscience
Identification and characterization of new inhibitors of fungal homoserine kinase.
Mcmaster University
Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility.
University of Pittsburgh