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29 articles for K Wu


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Structure-Based Discovery of Novel and Selective 5-Hydroxytryptamine 2B Receptor Antagonists for the Treatment of Irritable Bowel Syndrome.EBI
National Institute of Biological Sciences, Beijing
Novel pyrazoline derivatives as bi-inhibitor of COX-2 and B-Raf in treating cervical carcinoma.EBI
Second Affiliated Hospital of Southeast University
Discovery of novel 2,4-diarylaminopyrimidine analogues (DAAPalogues) showing potent inhibitory activities against both wild-type and mutant ALK kinases.EBI
Chinese Academy of Sciences
Novel 2,4-Diarylaminopyrimidine Analogues (DAAPalogues) Showing Potent c-Met/ALK Multikinase Inhibitory Activities.EBI
State Key Laboratory of Drug Research
Multisubstituted quinoxalines and pyrido[2,3-d]pyrimidines: synthesis and SAR study as tyrosine kinase c-Met inhibitors.EBI
China Pharmaceutical University
 
Further evidence for a dopamine reuptake pharmacophore. The effect of N-methylation on Threo-methylphenidate and its analogsEBI
TBA
Identification of new inhibitors of protein kinase R guided by statistical modeling.EBI
Weill Cornell Medical College
Application and challenges of nitrogen heterocycles in PROTAC linker.EBI
University of South China
High affinity and low PARP-trapping benzimidazole derivatives as a potential warhead for PARP1 degraders.EBI
University of South China
Discovery of 3,5-diaryl-1H-pyrazol-based ureas as potent RET inhibitors.EBI
Jinan University
Discovery and Design of Novel Cyclic Peptides as Specific Inhibitors Targeting CCN2 and Disrupting CCN2/EGFR Interaction for Kidney Fibrosis Treatment.EBI
Sun Yat-Sen University
Inhibition of cytosolic phospholipase A2alpha: hit to lead optimization.EBI
Wyeth Research
Identification of Nitric Oxide-Donating Ripasudil Derivatives with Intraocular Pressure Lowering and Retinal Ganglion Cell Protection Activities.EBI
Sun Yat-Sen University
Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities.EBI
Central South University
Discovery of N-substituted sulfamoylbenzamide derivatives as novel inhibitors of STAT3 signaling pathway based on Niclosamide.EBI
The First Affiliated Hospital of Wenzhou Medical University
Discovery of 4,6-pyrimidinediamine derivatives as novel dual EGFR/FGFR inhibitors aimed EGFR/FGFR1-positive NSCLC.EBI
Wenzhou Medical University
Design, synthesis and activity of novel 2,6-disubstituted purine derivatives, potential small molecule inhibitors of signal transducer and activator of transcription 3.EBI
Wenzhou Medical University
Synthesis and biological activity of 7-alkylidenecephems.EBI
Southern Methodist University
IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND THEIR USE IN THERAPYBDB
Imperial College Innovations
INHIBITORS OF MYELOPEROXIDASEBDB
Astrazeneca
PYRAZOLEAMIDE DERIVATIVESBDB
Hoffmann-La Roche
4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin specific protease 19 (USP19)BDB
Almac Discovery
Compounds and compositions for the treatment of parasitic diseasesBDB
Novartis
Substituted heteroaryls as inhibitors of the BCL6 BTB domain protein-protein interactionBDB
Ontario Institute For Cancer Research (Oicr)
Azaspirocycles as monoacylglycerol lipase modulatorsBDB
Janssen Pharmaceutica
Inhibitors of RAF kinasesBDB
Kinnate Biopharma
Heteroaryl inhibitors of PDE4BDB
Tetra Discovery Partners
Aminopyrimidine compound and composition comprising same and use thereofBDB
Shenzhen Targetrx