18 articles for AM Petros
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Turning a Substrate Peptide into a Potent Inhibitor for the Histone Methyltransferase SETD8.
Abbvie
Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity.
Abbvie
Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein.
Research & Development, Abbvie
Discovery and development of potent and selective inhibitors of histone methyltransferase g9a.
Abbvie
Cracking the molecular weight barrier: fragment screening of an aminotransferase using an NMR-based functional assay.
Abbott Laboratories
Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMR.
Abbott Laboratories
Discovery and structure-activity relationship of antagonists of B-cell lymphoma 2 family proteins with chemopotentiation activity in vitro and in vivo.
Abbott Laboratories
Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design.
Abbvie
Retention of immunosuppressant activity in an ascomycin analogue lacking a hydrogen-bonding interaction with FKBP12.
Abbott Laboratories
Targeting lysine specific demethylase 4A (KDM4A) tandem TUDOR domain - A fragment based approach.
Abbvie
Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors.
Abbvie
Imidazo[1,2-a]pyridines and imidazo[1,2-b]pyridazines as mark inhibitors
Merck Sharp & Dohme
5HT4(a) and 5-HT4(b) receptors have nearly identical pharmacology and are both expressed in human atrium and ventricle.
University of Oslo