BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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9 articles for WJ McClellan

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Conformationally defined adrenergic agents. 1. Design and synthesis of novel alpha 2 selective adrenergic agents: electrostatic repulsion based conformational prototypes.EBI
TBA
Discovery and structure-activity relationship of antagonists of B-cell lymphoma 2 family proteins with chemopotentiation activity in vitro and in vivo.EBI
Abbott Laboratories
Naphthamidine urokinase plasminogen activator inhibitors with improved pharmacokinetic properties.EBI
Abbott Laboratories
Interaction with the S1 beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors.EBI
Abbott Laboratories
Discovery of a Potent and Selective Covalent p300/CBP Inhibitor.EBI
Abbvie
Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors.EBI
Abbvie
Nrf2 regulatorsBDB
Glaxosmithkline
InhibitorsBDB
Probiodrug
5HT4(a) and 5-HT4(b) receptors have nearly identical pharmacology and are both expressed in human atrium and ventricle.BDB
University of Oslo