47 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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Diarylpyrazole compound, composition comprising same, and use thereof

Shenzhen Targetrx
METHODS AND COMPOSITIONS COMPRISING A BRAF INHIBITOR AND A PD-1 BINDING ANTAGONIST

Hoffmann-La Roche
METHYLQUINAZOLINONE DERIVATIVES

Hoffmann-La Roche
ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF

Sichuan Kelun-Biotech Biopharmaceutical
COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

Plexxikon
Compounds and compositions as protein kinase inhibitors

Array Biopharma
Methods and compositions of 4-substituted benzoylpiperazine-1-substituted carbonyls as β-catenin/B-cell lymphoma 9 inhibitors

University of Utah
Fused bicyclic (hetero)aromatic compounds useful for the treatment of cancers

Jazz Pharmaceuticals Ireland
Thieno[3,2-d]pyrimidine derivative compound having inhibitory activity for protein kinase

Hanmi Pharm.
Compounds for the treatment of BRAF-associated diseases and disorders

Array Biopharma
Compounds and methods for kinase modulation, and indications therefor

Plexxikon
Imidazooxazole derivative having antitumor effect, and pharmaceutical composition including same

Korea Institute of Science and Technology
1,2-dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions

Sabila Biosciences
Certain chemical entities, compositions, and methods

Neupharma
Biaryl amide compounds as kinase inhibitors

Novartis
Certain chemical entities, compositions, and methods

Neupharma
Imidazooxazole derivative having antitumor effect, and pharmaceutical composition including same

Korea Institute of Science and Technology
Compounds and compositions as protein kinase inhibitors

Array Biopharma
Fused tricyclic compounds as Raf kinase inhibitors

Beigene
Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases

Hanmi Pharm.
3-acetylenyl-pyrazole-pyrimidine derivative, and preparation method therefor and uses thereof

St. Chuan University
Fused tricyclic compounds as Raf kinase inhibitors

Beigene
Biaryl amide compounds as kinase inhibitors

Novartis
RAF kinase modulator compounds and methods of use thereof

Ambit Biosciences
Compounds and methods for kinase modulation, and indications therefor

Plexxikon
Fused tetra or penta-cyclic dihydrodiazepinocarbazolones as PARP inhibitors

Beigene
Fused tricyclic amide compounds as multiple kinase inhibitors

Beigene
Furanone compounds as kinase inhibitors

Eternity Bioscience
Kinase modulators for the treatment of cancer

Synovo
Isoquinoline-5-carboxamide derivative having inhibitory activity for protein kinase

Hanmi Pharm.
PI3K and/or mTOR inhibitor

Xuanzhu Pharma
Design and synthesis of new 2-anilinoquinolines bearing N-methylpicolinamide moiety as potential antiproliferative agents.

Korea Institute of Science and Technology
Raf inhibitor compounds

Deciphera Pharmaceuticals
Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases

Hanmi Pharm.
Sorafenib derivatives as sEH inhibitors

University of California
Azaindolylphenyl sulfonamides as serine/threonine kinase inhibitors

Boehringer Ingelheim International
Quinazoline compounds as kinase inhibitors

Development Center For Biotechnology
Pyrido [5, 4-D] pyrimidines as cell proliferation inhibitors

Boehringer Ingelheim International
Identification of type II inhibitors targeting BRAF using privileged pharmacophores.

Shanghai Institute of Pharmaceutical Industry
Pyrimido [5,4-D] pyrimidine derivatives for the inhibition of tyrosine kinases

Boehringer Ingelheim International
Compounds and compositions as protein kinase inhibitors

Novartis
Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinoline.

Amgen
Pyridoimidazolones as novel potent inhibitors of v-Raf murine sarcoma viral oncogene homologue B1 (BRAF).

The Institute of Cancer Research
Design and Synthesis of Orally Bioavailable Benzimidazoles as Raf Kinase Inhibitors.

Novartis
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity.

Plexxikon
Novel inhibitors of the v-raf murine sarcoma viral oncogene homologue B1 (BRAF) based on a 2,6-disubstituted pyrazine scaffold.

Cancer Research Uk Centre For Cancer Therapeutics
Biaryl amide compounds as kinase inhibitors

Novartis