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BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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47 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Diarylpyrazole compound, composition comprising same, and use thereofBDB
Shenzhen Targetrx
METHODS AND COMPOSITIONS COMPRISING A BRAF INHIBITOR AND A PD-1 BINDING ANTAGONISTBDB
Hoffmann-La Roche
METHYLQUINAZOLINONE DERIVATIVESBDB
Hoffmann-La Roche
ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOFBDB
Sichuan Kelun-Biotech Biopharmaceutical
COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFORBDB
Plexxikon
Compounds and compositions as protein kinase inhibitorsBDB
Array Biopharma
Methods and compositions of 4-substituted benzoylpiperazine-1-substituted carbonyls as β-catenin/B-cell lymphoma 9 inhibitorsBDB
University of Utah
Fused bicyclic (hetero)aromatic compounds useful for the treatment of cancersBDB
Jazz Pharmaceuticals Ireland
Thieno[3,2-d]pyrimidine derivative compound having inhibitory activity for protein kinaseBDB
Hanmi Pharm.
Compounds for the treatment of BRAF-associated diseases and disordersBDB
Array Biopharma
Compounds and methods for kinase modulation, and indications thereforBDB
Plexxikon
Imidazooxazole derivative having antitumor effect, and pharmaceutical composition including sameBDB
Korea Institute of Science and Technology
1,2-dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditionsBDB
Sabila Biosciences
Certain chemical entities, compositions, and methodsBDB
Neupharma
Biaryl amide compounds as kinase inhibitorsBDB
Novartis
Certain chemical entities, compositions, and methodsBDB
Neupharma
Imidazooxazole derivative having antitumor effect, and pharmaceutical composition including sameBDB
Korea Institute of Science and Technology
Compounds and compositions as protein kinase inhibitorsBDB
Array Biopharma
Fused tricyclic compounds as Raf kinase inhibitorsBDB
Beigene
Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinasesBDB
Hanmi Pharm.
3-acetylenyl-pyrazole-pyrimidine derivative, and preparation method therefor and uses thereofBDB
St. Chuan University
Fused tricyclic compounds as Raf kinase inhibitorsBDB
Beigene
Biaryl amide compounds as kinase inhibitorsBDB
Novartis
RAF kinase modulator compounds and methods of use thereofBDB
Ambit Biosciences
Compounds and methods for kinase modulation, and indications thereforBDB
Plexxikon
Fused tetra or penta-cyclic dihydrodiazepinocarbazolones as PARP inhibitorsBDB
Beigene
Fused tricyclic amide compounds as multiple kinase inhibitorsBDB
Beigene
Furanone compounds as kinase inhibitorsBDB
Eternity Bioscience
Kinase modulators for the treatment of cancerBDB
Synovo
Isoquinoline-5-carboxamide derivative having inhibitory activity for protein kinaseBDB
Hanmi Pharm.
PI3K and/or mTOR inhibitorBDB
Xuanzhu Pharma
Design and synthesis of new 2-anilinoquinolines bearing N-methylpicolinamide moiety as potential antiproliferative agents.BDB
Korea Institute of Science and Technology
Raf inhibitor compoundsBDB
Deciphera Pharmaceuticals
Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinasesBDB
Hanmi Pharm.
Sorafenib derivatives as sEH inhibitorsBDB
University of California
Azaindolylphenyl sulfonamides as serine/threonine kinase inhibitorsBDB
Boehringer Ingelheim International
Quinazoline compounds as kinase inhibitorsBDB
Development Center For Biotechnology
Pyrido [5, 4-D] pyrimidines as cell proliferation inhibitorsBDB
Boehringer Ingelheim International
Identification of type II inhibitors targeting BRAF using privileged pharmacophores.BDB
Shanghai Institute of Pharmaceutical Industry
Pyrimido [5,4-D] pyrimidine derivatives for the inhibition of tyrosine kinasesBDB
Boehringer Ingelheim International
Compounds and compositions as protein kinase inhibitorsBDB
Novartis
Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinoline.BDB
Amgen
Pyridoimidazolones as novel potent inhibitors of v-Raf murine sarcoma viral oncogene homologue B1 (BRAF).BDB
The Institute of Cancer Research
Design and Synthesis of Orally Bioavailable Benzimidazoles as Raf Kinase Inhibitors.BDB
Novartis
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity.BDB
Plexxikon
Novel inhibitors of the v-raf murine sarcoma viral oncogene homologue B1 (BRAF) based on a 2,6-disubstituted pyrazine scaffold.BDB
Cancer Research Uk Centre For Cancer Therapeutics
Biaryl amide compounds as kinase inhibitorsBDB
Novartis