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Thermodynamic properties of leukotriene A

Goethe-University Frankfurt
N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor¿ Modulators.

Goethe-University Frankfurt
Multi-dimensional target profiling of N,4-diaryl-1,3-thiazole-2-amines as potent inhibitors of eicosanoid metabolism.

Goethe-University Frankfurt
Development and evaluation of ST-1829 based on 5-benzylidene-2-phenylthiazolones as promising agent for anti-leukotriene therapy.

Goethe-University Frankfurt
Extending the structure-activity relationship of anthranilic acid derivatives as farnesoid X receptor modulators: development of a highly potent partial farnesoid X receptor agonist.

Goethe-University Frankfurt
Exploring the chemical space of multitarget ligands using aligned self-organizing maps.

Goethe University
Synthesis and structure-activity relationship studies of novel dual inhibitors of soluble epoxide hydrolase and 5-lipoxygenase.

Goethe-University Frankfurt
Design and synthesis of dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors.

Zafes/Liff/Osf Goethe-University Frankfurt
Dual-target virtual screening by pharmacophore elucidation and molecular shape filtering.

TBA
Synthesis and biological evaluation of a class of 5-benzylidene-2-phenyl-thiazolinones as potent 5-lipoxygenase inhibitors.

Zafes/Liff/Osf Goethe-University Frankfurt
A class of 5-benzylidene-2-phenylthiazolinones with high potency as direct 5-lipoxygenase inhibitors.

Goethe-University Frankfurt
SAR-study on a new class of imidazo[1,2-a]pyridine-based inhibitors of 5-lipoxygenase.

Zafes/Liff/Osf Goethe-University Frankfurt
Bioactivity-guided mapping and navigation of chemical space.

Institut FüR Molekulare Physiologie
Development of a Potent and Selective G2A (GPR132) Agonist.

Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening.

Johann Wolfgang Goethe-UniversitäT
Synthesis of thieno[2,3-b]pyridinones acting as cytoprotectants and as inhibitors of [3H]glycine binding to the N-methyl-D-aspartate (NMDA) receptor.

Johann Wolfgang Goethe University
Extraction and visualization of potential pharmacophore points using support vector machines: application to ligand-based virtual screening for COX-2 inhibitors.

Johann Wolfgang Goethe-UniversitäT
Structure-Based Design of Dual Partial Peroxisome Proliferator-Activated Receptor γ Agonists/Soluble Epoxide Hydrolase Inhibitors.

Goethe-University
Discovery of Irbesartan Derivatives as BLT2 Agonists by Virtual Screening.

Fraunhofer Institute For Translational Medicine and Phamacology Itmp
Design, Synthesis, and Structure-Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase.

Goethe-University of Frankfurt
First Structure-Activity Relationship Study of Potent BLT2 Agonists as Potential Wound-Healing Promoters.

Fraunhofer Ime
l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC Are Potent Activators of PPARγ.

Goethe-University Frankfurt
Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain.

Goethe-University Frankfurt
Structure optimization of a new class of PPARγ antagonists.

Fraunhofer Institute For Molecular Biology and Applied Ecology Ime
Design of Dual Inhibitors of Soluble Epoxide Hydrolase and LTA

Goethe University Frankfurt
Computer-Aided Selective Optimization of Side Activities of Talinolol.

Goethe-University of Frankfurt
Boosting Anti-Inflammatory Potency of Zafirlukast by Designed Polypharmacology.

Goethe University Frankfurt
A Dual Modulator of Farnesoid X Receptor and Soluble Epoxide Hydrolase To Counter Nonalcoholic Steatohepatitis.

Goethe-University Frankfurt
Arylpiperazine derivatives and methods of utilizing same

Reviva Pharmaceuticals
Thienopyrimidine ureas as novel and potent multitargeted receptor tyrosine kinase inhibitors.

Abbott Laboratories