BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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16 articles for LT Bacheler

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
 
Functionalized aliphatic P2/P2′ analogs of HIV-1 protease inhibitor DMP323EBI
TBA
 
Synthesis of (+)-biotin derivatives as HIV-1 protease inhibitorsEBI
TBA
Synthesis, antiviral activity and pharmacokinetics of P1/P1' substituted 3-aminoindazole cyclic urea HIV protease inhibitors.EBI
Bristol-Myers Squibb
Unsymmetrical cyclic ureas as HIV-1 protease inhibitors: novel biaryl indazoles as P2/P2' substituents.EBI
Dupont Pharmaceuticals
The synthesis and evaluation of cyclic ureas as HIV protease inhibitors: modifications of the P1/P1' residues.EBI
Dupont Pharmaceuticals
Nonsymmetric P2/P2' cyclic urea HIV protease inhibitors. Structure-activity relationship, bioavailability, and resistance profile of monoindazole-substituted P2 analogues.EBI
Dupont Pharmaceuticals
Cyclic urea amides: HIV-1 protease inhibitors with low nanomolar potency against both wild type and protease inhibitor resistant mutants of HIV.EBI
Dupont Pharmaceuticals
Aryl sultam derivatives as RORc modulatorsBDB
Genentech
Compositions, methods, and systems for the synthesis and use of imaging agentsBDB
Lantheus Medical Imaging
Substituted 1,7-naphthyridines as dopamine D1 ligandsBDB
Pfizer
Fused tricyclic amide compounds as multiple kinase inhibitorsBDB
Beigene
Heteroaryl compounds and methods of use thereofBDB
Sunovion Pharmaceuticals
PRMT5 inhibitors and uses thereofBDB
Epizyme
5-chloro-3-(phenylsulfonyl)indole-2-carboxamide: a novel, non-nucleoside inhibitor of HIV-1 reverse transcriptase.BDB
Merck Research Laboratories
Aminodiol HIV protease inhibitors. Synthesis and structure-activity relationships of P1/P1' compounds: correlation between lipophilicity and cytotoxicity.BDB
Bristol-Myers Squibb
Synthesis and structure-activity relationships of a series of penicillin-derived HIV proteinase inhibitors containing a stereochemically unique peptide isostere.BDB
Glaxo Group Research