16 articles for H Du
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
Organization
A novel quantitative structure-activity relationship method to predict the affinities of MT3 melatonin binding site.

Lanzhou University
SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors.

Exelixis
Discovery and characterization of an inhibitor of glucosylceramide synthase.

Exelixis
The design, synthesis, and biological evaluation of PIM kinase inhibitors.

Exelixis
Discovery of XL413, a potent and selective CDC7 inhibitor.

Exelixis
Discovery of a new class of glucosylceramide synthase inhibitors.

Exelixis
Discovery of HC-7366: An Orally Bioavailable and Efficacious GCN2 Kinase Activator.

Pharmaron UK Ltd.
Discovery of Highly Potent Small-Molecule PD-1/PD-L1 Inhibitors with a Novel Scaffold for Cancer Immunotherapy.

China Pharmaceutical University
Discovery of 6-Formylpyridyl Urea Derivatives as Potent Reversible-Covalent Fibroblast Growth Factor Receptor 4 Inhibitors with Improved Anti-Hepatocellular Carcinoma Activity.

Jinan University
Discovery of 2-amino-3-amido-5-aryl-pyridines as highly potent, orally bioavailable, and efficacious PERK kinase inhibitors.

Hibercell
Novel deoxyvasicinone and tetrahydro-beta-carboline hybrids as inhibitors of acetylcholinesterase and amyloid beta aggregation.

Xinyang Normal University
A 18β-glycyrrhetinic acid conjugate with Vorinostat degrades HDAC3 and HDAC6 with improved antitumor effects.

Shenyang Pharmaceutical University
CN128: A New Orally Active Hydroxypyridinone Iron Chelator.

Zhejiang University
Synthesis and biological evaluation of tryptophan-derived rhodanine derivatives as PTP1B inhibitors and anti-bacterial agents.

Yanbian University College of Pharmacy
Novel deoxyvasicinone derivatives as potent multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation.

Xinyang Normal University
IRAK degraders and uses thereof

Kymera Therapeutics