39 articles for M Schubert-Zsilavecz
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
Organization
N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor¿ Modulators.
Goethe-University Frankfurt
Anthranilic acid derivatives as nuclear receptor modulators--development of novel PPAR selective and dual PPAR/FXR ligands.
Goethe-University Frankfurt
Fragmentation of GW4064 led to a highly potent partial farnesoid X receptor agonist with improved drug-like properties.
Goethe-University Frankfurt
SAR-studies of¿-secretase modulators with PPAR¿-agonistic and 5-lipoxygenase-inhibitory activity for Alzheimer's disease.
Goethe-University Frankfurt
Identification of pirinixic acid derivatives bearing a 2-aminothiazole moiety combines dual PPARa/¿ activation and dual 5-LO/mPGES-1 inhibition.
Goethe-University Frankfurt
Molecular determinants for improved activity at PPARa: structure-activity relationship of pirinixic acid derivatives, docking study and site-directed mutagenesis of PPARa.
Goethe-University Frankfurt
Extending the structure-activity relationship of anthranilic acid derivatives as farnesoid X receptor modulators: development of a highly potent partial farnesoid X receptor agonist.
Goethe-University Frankfurt
Anthranilic acid derivatives as novel ligands for farnesoid X receptor (FXR).
Goethe-University Frankfurt
Synthesis and pharmacological characterization of benzenesulfonamides as dual species inhibitors of human and murine mPGES-1.
Goethe-University Frankfurt
Aminothiazole-featured pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors with improved potency and efficiency in vivo.
Goethe-University Frankfurt
Design and synthesis of dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors.
Zafes/Liff/Osf Goethe-University Frankfurt
Discovery and biological evaluation of a novel class of dual microsomal prostaglandin E2 synthase-1/5-lipoxygenase inhibitors based on 2-[(4,6-diphenethoxypyrimidin-2-yl)thio]hexanoic acid.
Zafes/Liff/Goethe University Frankfurt
Effect of phospholipid-based formulations of Boswellia serrata extract on the solubility, permeability, and absorption of the individual boswellic acid constituents present.
Central Laboratory of German Pharmacists
Structure-activity relationship of nonacidic quinazolinone inhibitors of human microsomal prostaglandin synthase 1 (mPGES 1).
Johann Wolfgang Goethe University
Acidic elements in histamine H(3) receptor antagonists.
Johann Wolfgang Goethe University
Pirinixic acid derivatives as novel dual inhibitors of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase.
Eberhard Karls University Tuebingen
SAR-study on a new class of imidazo[1,2-a]pyridine-based inhibitors of 5-lipoxygenase.
Zafes/Liff/Osf Goethe-University Frankfurt
Identification of 2-mercaptohexanoic acids as dual inhibitors of 5-lipoxygenase and microsomal prostaglandin E2 synthase-1.
Eberhard Karls University Tuebingen
A novel class of dual mPGES-1/5-LO inhibitors based on thea-naphthyl pirinixic acid scaffold.
Goethe-University Frankfurt
Design, synthesis, and biological evaluation of a novel class of gamma-secretase modulators with PPARgamma activity.
Zafes/Liff/Goethe University Frankfurt
Truxillic acid derivatives act as peroxisome proliferator-activated receptor gamma activators.
Goethe-University Frankfurt
Rational design of a pirinixic acid derivative that acts as subtype-selective PPARgamma modulator.
Goethe-University Frankfurt
Discovery of a novel class of 2-mercaptohexanoic acid derivatives as highly active PPARalpha agonists.
Goethe-University Frankfurt
An innovative method to study target protein-drug interactions by mass spectrometry.
Martin-Luther-UniversitäT Halle-Wittenberg
Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3.
Goethe University Frankfurt
Development of a Potent and Selective G2A (GPR132) Agonist.
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
Structural Fusion of Natural and Synthetic Ligand Features Boosts RXR Agonist Potency.
Goethe University Frankfurt
Rational Design of a New RXR Agonist Scaffold Enabling Single-Subtype Preference for RXRα, RXRβ, and RXRγ.
Goethe University Frankfurt
The Medicinal Chemistry and Therapeutic Potential of LRH-1 Modulators.
Goethe University Frankfurt
Design, Synthesis, and Structure-Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase.
Goethe-University of Frankfurt
First Structure-Activity Relationship Study of Potent BLT2 Agonists as Potential Wound-Healing Promoters.
Fraunhofer Ime
l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC Are Potent Activators of PPARγ.
Goethe-University Frankfurt
Structure optimization of a new class of PPARγ antagonists.
Fraunhofer Institute For Molecular Biology and Applied Ecology Ime
A Selective Modulator of Peroxisome Proliferator-Activated Receptor γ with an Unprecedented Binding Mode.
Goethe-University Frankfurt
Vanillin-derived antiproliferative compounds influence Plk1 activity.
Johann-Wolfgang-Goethe University of Frankfurt
Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E
Goethe-University Frankfurt
