BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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11 articles for LC Cantley

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
a-Ketothioamide Derivatives: A Promising Tool to Interrogate Phosphoglycerate Dehydrogenase (PHGDH).EBI
University of Louvain
2-Oxo-N-aryl-1,2,3,4-tetrahydroquinoline-6-sulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase.EBI
National Human Genome Research Institute
Slow self-activation enhances the potency of viridin prodrugs.EBI
Harvard Medical School
Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease.EBI
University of Dundee
Development of potent and selective degraders of PI5P4Kγ.EBI
Stanford University
Discovery and Structure-Activity Relationship Study of (EBI
Dana-Farber Cancer Institute
Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells.EBI
Meyer Cancer Center
Structure-Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors.EBI
Dana-Farber Cancer Institute
Discovery and optimization of aspartate aminotransferase 1 inhibitors to target redox balance in pancreatic ductal adenocarcinoma.EBI
California Institute For Biomedical Research
HETEROCYCLIC INHIBITORS OF IGF-1R FOR TREATMENT OF DISEASEBDB
Horizon Therapeutics Ireland Dac
TLR8 agonistBDB
Chia Tai Tianqing Pharmaceutical Group