BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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10 articles for JC Sacchettini

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Mycobacterium tuberculosis dihydrofolate reductase is not a target relevant to the antitubercular activity of isoniazid.EBI
Texas A&M University
PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas.EBI
University of North Carolina at Chapel Hill
Synthesis and biological activity of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 2: 2'-substituted triclosan derivatives.EBI
Jacobus Pharmaceutical
Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-substituted triclosan derivatives.EBI
Jacobus Pharmaceutical
In Vitro and In Vivo Inhibition of the EBI
University of North Carolina at Chapel Hill
Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target.EBI
University of Dundee
Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase.EBI
Texas A&M University
A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids.EBI
Baylor University
1-(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido [2, 3-B]pyrazin- 8-yl)oxy]phenyl]urea derivatives as RAF inhibitors for the treatment of cancerBDB
Cancer Research Technology
Substituted quinazoline compounds and uses thereof for modulating glucocerebrosidase activityBDB
Northwestern University