BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Donate Now

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

Advanced Search

24 articles for C Niu

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.EBI
Pharmasset
2'-deoxy-2'-a-fluoro-2'-ß-C-methyl 3',5'-cyclic phosphate nucleotide prodrug analogs as inhibitors of HCV NS5B polymerase: discovery of PSI-352938.EBI
Pharmasset
Optimization of 5-vinylaryl-3-pyridinecarbonitriles as PKCtheta inhibitors.EBI
Wyeth Research
First generation 5-vinyl-3-pyridinecarbonitrile PKCtheta inhibitors.EBI
Wyeth Research
C-5 Substituted heteroaryl 3-pyridinecarbonitriles as PKCtheta inhibitors: Part I.EBI
Wyeth Research
Optimization of 5-phenyl-3-pyridinecarbonitriles as PKCtheta inhibitors.EBI
Wyeth Research
Discovery of the catechol structural moiety as a Stat3 SH2 domain inhibitor by virtual screening.EBI
Wyeth Pharmaceuticals
Design, synthesis, and evaluation of inhibitors for severe acute respiratory syndrome 3C-like protease based on phthalhydrazide ketones or heteroaromatic esters.EBI
University of Alberta
Synthesis and biological activity of analogues of the antimicrotubule agent N,beta,beta-trimethyl-L-phenylalanyl-N(1)-[(1S,2E)-3-carboxy-1-isopropylbut-2-enyl]- N(1),3-dimethyl-L-valinamide (HTI-286).EBI
Wyeth Research
Neuroactive Type-A γ-Aminobutyric Acid Receptor Allosteric Modulator Steroids from the Hypobranchial Gland of Marine Mollusk, EBI
University of Utah
Acetylenic TACE inhibitors. Part 1. SAR of the acyclic sulfonamide hydroxamates.EBI
Wyeth Research
Discovery of GS-9688 (Selgantolimod) as a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment of Chronic Hepatitis B.EBI
Gilead Sciences
Highly Potent and Selective EBI
Purdue University
Synthesis and bioactivity of novel isoxazole chalcone derivatives on tyrosinase and melanin synthesis in murine B16 cells for the treatment of vitiligo.EBI
Chinese Academy of Sciences
Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands.EBI
TBA
Use of 2'-spirocyclic ethers in HCV nucleoside design.EBI
Pharmasset
Design and syntheses of novel phthalazin-1(2H)-one derivatives as acetohydroxyacid synthase inhibitors.EBI
Central China Normal University
The mechanism of action of beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine involves a second metabolic pathway leading to beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate, a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.EBI
Pharmasset
1H-imidazo[4,5-h]quinazoline compound as protein kinase inhibitorBDB
Shengke Pharmaceuticals (Jiangsu)
METHODS FOR INHIBITING PARASITIC GLUCOKINASE AND/OR HEXOKINASEBDB
University of South Carolina
PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORSBDB
Chiesi Farmaceutici
PHENYL TRIAZOLE MLL1-WDR5 PROTEIN-PROTEIN INTERACTION INHIBITORBDB
Huyabio International
Substituted pyrrolidines as factor XIa inhibitors for the treatment thromboembolic diseasesBDB
Ono Pharmaceutical
Highly potent, selective, and low cost bis-tetrahydroaminacrine inhibitors of acetylcholinesterase. Steps toward novel drugs for treating Alzheimer's disease.BDB
Mayo Foundation