77 articles for N Neamati
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
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Article Title
Organization
Design and discovery of 5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide inhibitors of HIV-1 integrase.
Shandong University
Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75.
South China Normal University
Discovery of small molecule integrin alphavbeta3 antagonists as novel anticancer agents.
University of Southern California
Synthesis and biological evaluation of dimeric RGD peptide-paclitaxel conjugate as a model for integrin-targeted drug delivery.
University of Southern California
Application of CoMFA and CoMSIA 3D-QSAR and docking studies in optimization of mercaptobenzenesulfonamides as HIV-1 integrase inhibitors.
University of Southern California
Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein.
University of Southern California
Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells.
University of Southern California
Inhibition of the strand transfer step of HIV-1 integrase by non-natural dinucleotides.
University of Georgia
Structure activity of 3-aryl-1,3-diketo-containing compounds as HIV-1 integrase inhibitors.
National Cancer Institute/Nih
Depsides and depsidones as inhibitors of HIV-1 integrase: discovery of novel inhibitors through 3D database searching.
National Cancer Institute-Bethesda
HIV-1 integrase pharmacophore: discovery of inhibitors through three-dimensional database searching.
National Cancer Institute-Bethesda
Curcumin analogs with altered potencies against HIV-1 integrase as probes for biochemical mechanisms of drug action.
National Cancer Institute-Bethesda
Antiretroviral agents as inhibitors of both human immunodeficiency virus type 1 integrase and protease.
National Cancer Institute-Bethesda
Discovery of novel small-molecule inhibitors of human epidermal growth factor receptor-2: combined ligand and target-based approach.
University of Southern California
Design of FK866-Based Degraders for Blocking the Nonenzymatic Functions of Nicotinamide Phosphoribosyltransferase.
Beijing University of Chinese Medicine
Pyrazolone derivatives as potent and selective small-molecule SIRT5 inhibitors.
University of Michigan
Design and Synthesis of Orally Active Quinolyl Pyrazinamides as Sigma 2 Receptor Ligands for the Treatment of Pancreatic Cancer.
University of Michigan
Ring substituent effects on biological activity of vinyl sulfones as inhibitors of HIV-1.
University of California
Inhibition of HIV-1 integrase activity by synthetic peptides derived from the HIV-1 HXB2 Pol region of the viral genome.
University of Southern California
Sequence-based design and discovery of peptide inhibitors of HIV-1 integrase: insight into the binding mode of the enzyme.
Graduate School of The Chinese Academy of Sciences
From ligand to complexes: inhibition of human immunodeficiency virus type 1 integrase by beta-diketo acid metal complexes.
Università
Dynamic pharmacophore model optimization: identification of novel HIV-1 integrase inhibitors.
University of Houston
Beta-diketo acids with purine nucleobase scaffolds: novel, selective inhibitors of the strand transfer step of HIV integrase.
University of Georgia
HIV integrase inhibitors with nucleobase scaffolds: discovery of a highly potent anti-HIV agent.
University of Georgia
Diketo acid pharmacophore. 2. Discovery of structurally diverse inhibitors of HIV-1 integrase.
University of Southern California
Synthesis and biological evaluation of geminal disulfones as HIV-1 integrase inhibitors.
University of California
Identification of 2-hydroxybenzoic acid derivatives as selective SIRT5 inhibitors.
University of Michigan
Dynamic receptor-based pharmacophore model development and its application in designing novel HIV-1 integrase inhibitors.
University of Houston
Beta-diketo acid pharmacophore hypothesis. 1. Discovery of a novel class of HIV-1 integrase inhibitors.
University of Southern California
Design and synthesis of novel indole beta-diketo acid derivatives as HIV-1 integrase inhibitors.
Università
Rational design and synthesis of novel dimeric diketoacid-containing inhibitors of HIV-1 integrase: implication for binding to two metal ions on the active site of integrase.
Institute of Materia Medica
Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy.
University of Michigan
Discovery, structure-activity relationship study and biological evaluation of 2-thioureidothiophene-3-carboxylates as a novel class of C-X-C chemokine receptor 2 (CXCR2) antagonists.
University of Michigan
Characterization of Aminobenzylphenols as Protein Disulfide Isomerase Inhibitors in Glioblastoma Cell Lines.
University of Michigan
Discovery of a Napabucasin PROTAC as an Effective Degrader of the E3 Ligase ZFP91.
University of Michigan
Discovery of a nuclease-resistant, non-natural dinucleotide that inhibits HIV-1 integrase.
The University of Iowa
Structure-Based Design of N-(5-Phenylthiazol-2-yl)acrylamides as Novel and Potent Glutathione S-Transferase Omega 1 Inhibitors.
Sichuan University
Design, Synthesis, and Biological Evaluation of Novel Allosteric Protein Disulfide Isomerase Inhibitors.
University of Michigan
Chicoric acid analogues as HIV-1 integrase inhibitors.
National Cancer Institute-Bethesda
Inhibition of HIV integrase by novel nucleotides bearing tricyclic bases.
University of Iowa
Salicylhydrazine-containing inhibitors of HIV-1 integrase: implication for a selective chelation in the integrase active site.
National Cancer Institute-Bethesda
Discovery of HIV-1 integrase inhibitors by pharmacophore searching.
National Cancer Institute-Bethesda
Synthesis, docking, and biological studies of phenanthrene β-diketo acids as novel HIV-1 integrase inhibitors.
University of Tennessee Health Science Center
Design and synthesis of novel pyrimidone analogues as HIV-1 integrase inhibitors.
Shandong University
Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction.
University of Southern California
Design of cell-permeable stapled peptides as HIV-1 integrase inhibitors.
Shanghai Institute of Materia Medica
Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction.
University of Southern California
Discovery of novel inhibitors of LEDGF/p75-IN protein-protein interactions.
University of Southern California
Repositioning HIV-1 integrase inhibitors for cancer therapeutics: 1,6-naphthyridine-7-carboxamide as a promising scaffold with drug-like properties.
Chinese Academy of Sciences
Design of HIV-1 integrase inhibitors targeting the catalytic domain as well as its interaction with LEDGF/p75: a scaffold hopping approach using salicylate and catechol groups.
Chinese Academy of Sciences
Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors.
University of Tennessee Health Science Center
Development of the next generation of HIV-1 integrase inhibitors: pyrazolone as a novel inhibitor scaffold.
University of Southern California
Design and synthesis of novel nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors from caffeic acid phenethyl ester.
Shandong University
Synthesis and anti-HIV-1 integrase activities of 3-aroyl-2,3-dihydro-1,1-dioxo-1,4,2-benzodithiazines.
Medical University of Gda?Sk
Amide-containing diketoacids as HIV-1 integrase inhibitors: synthesis, structure-activity relationship analysis, and biological activity.
Shandong University
Design and synthesis of novel dihydroquinoline-3-carboxylic acids as HIV-1 integrase inhibitors.
University of Sassari
Discovery of 3-acetyl-4-hydroxy-2-pyranone derivatives and their difluoridoborate complexes as a novel class of HIV-1 integrase inhibitors.
University of Southern California
Synthesis, anti-HIV-1 integrase, and cytotoxic activities of 4-chloro-N-(4-oxopyrimidin-2-yl)-2-mercaptobenzenesulfonamide derivatives.
Medical University of Gdansk
Efficient synthesis and utilization of phenyl-substituted heteroaromatic carboxylic acids as aryl diketo acid isosteres in the design of novel HIV-1 integrase inhibitors.
Chinese Academy of Sciences
Novel dimeric aryldiketo containing inhibitors of HIV-1 integrase: effects of the phenyl substituent and the linker orientation.
Chinese Academy of Sciences
Quinolone 3-carboxylic acid pharmacophore: design of second generation HIV-1 integrase inhibitors.
University of Southern California
Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors.
University of Southern California
Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore.
University of Southern California
Substituted 2-pyrrolinone inhibitors of HIV-1 integrase.
University of Southern California
Synthesis and biological evaluation of novel 5(H)-phenanthridin-6-ones, 5(H)-phenanthridin-6-one diketo acid, and polycyclic aromatic diketo acid analogs as new HIV-1 integrase inhibitors.
University of Tennessee Health Science Center
Design, Synthesis, and Biological Evaluation of 4-Quinoline Carboxylic Acids as Inhibitors of Dihydroorotate Dehydrogenase.
University of Michigan
Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy.
Indiana University School of Medicine
