16 articles for R Brenk
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
Organization
Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasis.
University of Dundee
The design and synthesis of potent and selective inhibitors of Trypanosoma brucei glycogen synthase kinase 3 for the treatment of human african trypanosomiasis.
University of Dundee
Virtual fragment screening for novel inhibitors of 6-phosphogluconate dehydrogenase.
University of Dundee
Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sickness.
University of Dundee
Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors.
University of Dundee
Design, synthesis, and biological evaluation of 3,4-diarylmaleimides as angiogenesis inhibitors.
Johannes Gutenberg University
Virtual screening for submicromolar leads of tRNA-guanine transglycosylase based on a new unexpected binding mode detected by crystal structure analysis.
Philipps-UniversitäT Marburg
How To Design Selective Ligands for Highly Conserved Binding Sites: A Case Study Using
Johannes Gutenberg-Universit£T Mainz
A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors.
University of Dundee
Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors.
University of Dundee
Peptidomimetic 2-cyanopyrrolidines as potent selective cathepsin L inhibitors.
The M. S. University of Baroda
Potent and selective Aurora inhibitors identified by the expansion of a novel scaffold for protein kinase inhibition.
Nerviano Medical Sciences