The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 772K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

8 articles for JC McKew


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
64
Reactions of functionalized sulfonamides: application to lowering the lipophilicity of cytosolic phospholipase A2alpha inhibitors.EBI
Wyeth Research
21
Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model.EBI
Wyeth Research
37
Discovery of Ecopladib, an indole inhibitor of cytosolic phospholipase A2alpha.EBI
Wyeth Research
20
1,2,4-Oxadiazolidin-3,5-diones and 1,3,5-triazin-2,4,6-triones as cytosolic phospholipase A2alpha inhibitors.EBI
Wyeth Research
46
Inhibition of cytosolic phospholipase A2alpha: hit to lead optimization.EBI
Wyeth Research
22
Structure-activity relationships of indole cytosolic phospholipase A(2)alpha inhibitors: substrate mimetics.EBI
Wyeth Research
169
Purine derivatives as CB2 receptor agonistsBDB
Hoffmann-La Roche
25
5-Amidinoindoles as dual inhibitors of coagulation factors IXa and Xa.BDB
Bristol Myers Squibb