BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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24 articles for T Heinrich

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Novel reversible methionine aminopeptidase-2 (MetAP-2) inhibitors based on purine and related bicyclic templates.EBI
Merck
Discovery of novel 7-azaindoles as PDK1 inhibitors.EBI
Merck
Fragment-based discovery of focal adhesion kinase inhibitors.EBI
Merck
Synthesis and biological evaluation of novel propargyl amines as potential fluorine-18 labeled radioligands for detection of MAO-B activity.EBI
Karolinska Institutet
Fragment-based discovery of new highly substituted 1H-pyrrolo[2,3-b]- and 3H-imidazolo[4,5-b]-pyridines as focal adhesion kinase inhibitors.EBI
Merck Serono
Synthesis and evaluation of [¹8F]fluororasagiline, a novel positron emission tomography (PET) radioligand for monoamine oxidase B (MAO-B).EBI
Karolinska Institutet
Synthesis of three novel fluorine-18 labeled analogues of L-deprenyl for positron emission tomography (PET) studies of monoamine oxidase B (MAO-B).EBI
Karolinska Institutet
Syntheses of novel 2,3-diaryl-substituted 5-cyano-4-azaindoles exhibiting c-Met inhibition activity.EBI
Technical University of Darmstadt
Structure-kinetic relationship reveals the mechanism of selectivity of FAK inhibitors over PYK2.EBI
Goethe University Frankfurt
MSC-1186, a Highly Selective Pan-SRPK Inhibitor Based on an Exceptionally Decorated Benzimidazole-Pyrimidine Core.EBI
Goethe University Frankfurt
Discovery of 5-{2-[5-Chloro-2-(5-ethoxyquinoline-8-sulfonamido)phenyl]ethynyl}-4-methoxypyridine-2-carboxylic Acid, a Highly Selective in Vivo Useable Chemical Probe to Dissect MCT4 Biology.EBI
Merck Healthcare
Optimization of TEAD P-Site Binding Fragment Hit into In Vivo Active Lead EBI
Merck Healthcare
Synthesis and structure--activity relationship in a class of indolebutylpiperazines as dual 5-HT(1A) receptor agonists and serotonin reuptake inhibitors.EBI
Merck
Indolebutylamines as selective 5-HT(1A) agonists.EBI
Merck
Identification of Methionine Aminopeptidase-2 (MetAP-2) Inhibitor EBI
Merck Healthcare
Discovery and Structure-Based Optimization of Next-Generation Reversible Methionine Aminopeptidase-2 (MetAP-2) Inhibitors.EBI
Merck Healthcare
Discovery of BAY-985, a Highly Selective TBK1/IKKε Inhibitor.EBI
Bayer
Development of a novel fluorine-18 labeled deuterated fluororasagiline ([(18)F]fluororasagiline-D2) radioligand for PET studies of monoamino oxidase B (MAO-B).EBI
Karolinska Institutet
COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSESBDB
Clear Creek Bio
Inhibitors of tryptophan dioxygenases (IDO1 and TDO) and their use in therapyBDB
Auckland Uniservices
Cinnoline derivatives useful as CB-1 receptor inverse agonistsBDB
Janssen Pharmaceutica
Fused pyrimidine compound, and preparation method, intermediate, composition, and uses thereofBDB
Shanghai Yingli Pharmaceutical
Boron-based inhibitors of acyl protein thioesterases 1 and 2.BDB
Technical University of Dortmund