BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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27 articles for B Bader

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction.EBI
Bayer AG
Novel Mps1 Kinase Inhibitors with Potent Antitumor Activity.EBI
Bayer Pharma AG
Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target.EBI
Bayer AG
BAY-8400: A Novel Potent and Selective DNA-PK Inhibitor which Shows Synergistic Efficacy in Combination with Targeted Alpha Therapies.EBI
Bayer
Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase.EBI
Bayer
Damage Incorporated: Discovery of the Potent, Highly Selective, Orally Available ATR Inhibitor BAY 1895344 with Favorable Pharmacokinetic Properties and Promising Efficacy in Monotherapy and in Combination Treatments in Preclinical Tumor Models.EBI
Bayer
Discovery of BAY-985, a Highly Selective TBK1/IKKε Inhibitor.EBI
Bayer
CRYSTAL FORM OF PYRROLOPYRIMIDINE COMPOUND AND PREPARATION METHOD FOR CRYSTAL FORMBDB
Zhejiang Longcharm Bio-Tech Pharma. Co.
Compounds and probes for imaging huntingtin proteinBDB
CHDI Foundation, Inc.
Leucine-rich repeat kinase 2 (LRRK2) inhibitorsBDB
H. Lundbeck
SMALL-MOLECULE MODULATORS OF THE ORPHAN NUCLEAR RECEPTOR TLXBDB
Baylor College of Medicine
GALECTIN-3 INHIBITING 2-HYDROXYCYCLOALKANE-1-CARBAMOYL DERIVATIVESBDB
Idorsia Pharmaceuticals
Crystalline succinate salt of 6-(6-aminopyrazin-2-yl)-n-(4-(4-(oxetan-3-yl)piperazin-1-yl)phenyl)imidazo[1,2-a]pyrazin-8-amineBDB
Kronos Bio
Inhibitors of tryptophan dioxygenases (IDO1 and TDO) and their use in therapyBDB
Auckland Uniservices
Substituted [5,6]cyclic-4(3H)-pyrimidinones as anticancer agentsBDB
Zenji Research Laboratories
Imidazolepyridine compounds and uses thereofBDB
Novartis
GLS1 inhibitors for treating diseaseBDB
The University of Texas System
Cinnoline derivatives useful as CB-1 receptor inverse agonistsBDB
Janssen Pharmaceutica
Molecular docking studies and biological evaluation of 1,3,4-thiadiazole derivatives bearing Schiff base moieties as tyrosinase inhibitors.BDB
Shaoyang University
Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereofBDB
Kissei Pharmaceutical
Design, synthesis, biological evaluation, and molecular docking of novel benzopyran and phenylpyrazole derivatives as Akt inhibitors.BDB
Zhejiang University
Selective androgen receptor modulatorsBDB
Radius Health
Histone deacetylase inhibitors, process for preparation and uses thereofBDB
Zhejiang Hisun Pharmaceutical
Heterocyclic pyrazole compounds, method for preparing the same and use thereofBDB
Development Center For Biotechnology
Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activityBDB
Neuraxon
Urokinase inhibitors, production and use thereofBDB
The Medicines