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23 articles for R Jones


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptor.EBI
Pfizer
Synthesis and Cardiac Imaging of (18)F-Ligands Selective for ß1-Adrenoreceptors.EBI
TBA
The discovery of long acting beta2-adrenoreceptor agonists.EBI
Pfizer
Mapping the melatonin receptor. 6. Melatonin agonists and antagonists derived from 6H-isoindolo[2,1-a]indoles, 5,6-dihydroindolo[2,1-a]isoquinolines, and 6,7-dihydro-5H-benzo[c]azepino[2,1-a]indoles.EBI
King'S College London
An in situ oxidation strategy towards overcoming hERG affinity.EBI
Pfizer
Discovery of quinazoline HPK1 inhibitors with high cellular potency.EBI
Emd Serono Research & Development Institute
Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer.EBI
Pfizer
Identification of Clinical Candidate M2698, a Dual p70S6K and Akt Inhibitor, for Treatment of PAM Pathway-Altered Cancers.EBI
Emd Serono Research & Development Institute
Discovery of potent and selective reversible Bruton's tyrosine kinase inhibitors.EBI
Emd Serono Research & Development Institute
The Discovery of a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor (PF-06273340) for the Treatment of Pain.EBI
Pfizer
Discovery of Lanraplenib (GS-9876): A Once-Daily Spleen Tyrosine Kinase Inhibitor for Autoimmune Diseases.EBI
Gilead Sciences
Mapping the melatonin receptor. 3. Design and synthesis of melatonin agonists and antagonists derived from 2-phenyltryptamines.EBI
University College London
Discovery of a novel series of pyridine and pyrimidine carboxamides as potent and selective covalent inhibitors of Btk.EBI
Emd Serono Research & Development Institute
Optimization of the efflux ratio and permeability of covalent irreversible BTK inhibitors.EBI
Emd Serono Research & Development Institute
Discovery of potent, highly selective covalent irreversible BTK inhibitors from a fragment hit.EBI
Emd Serono Research & Development Institute
Discovery of Potent and Orally Bioavailable Macrocyclic Peptide-Peptoid Hybrid CXCR7 Modulators.EBI
Pfizer
NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS, COMBINATIONS AND USES RELATED THERETOBDB
Emory University
Macrocyclic immunomodulatorsBDB
Chemocentryx
Compounds as inhibitors of DNA methyltransferasesBDB
FundaciÓN Para La InvestigaciÓN MÉDica Aplicada
Heterocyclic compounds and their use as dopamine D1 ligandsBDB
Pfizer
Kinase inhibitorsBDB
Allergan
Pyrimidooxazocine derivatives as mTOR-inhibitorsBDB
Sanofi