Binding Database

BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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10 articles for ES Furfine

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: the discovery of GW0385.

Glaxosmithkline

N-Phenylamidines as selective inhibitors of human neuronal nitric oxide synthase: structure-activity studies and demonstration of in vivo activity.

Glaxo Wellcome Research and Development

Substituted N-phenylisothioureas: potent inhibitors of human nitric oxide synthase with neuronal isoform selectivity.

Glaxo Wellcome Research and Development

Conformationally restricted arginine analogues as inhibitors of human nitric oxide synthase

TBA

Exploration of the P1 SAR of aldehyde cathepsin K inhibitors.

Glaxosmithkline

BTK Inhibitors

Merck Sharp & Dohme

Non-nucleoside reverse transcriptase inhibitors

Merck Sharp & Dohme

Androgen receptor antagonists

University of California

Tetrahydro-benzodiazepinones

Hoffmann-La Roche

Phenethylthiazolylthiourea (PETT) compounds as a new class of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs.

Eli Lilly