36 articles for Q Dong
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Discovery of TAK-659 an orally available investigational inhibitor of Spleen Tyrosine Kinase (SYK).
Takeda California
Discovery of potent and orally bioavailable inhibitors of Human Uric Acid Transporter 1 (hURAT1) and binding mode prediction using homology model.
Shanghai Hengrui Pharmaceutical
Synthesis and biological evaluation of cyclopentyl-triazolol-pyrimidine (CPTP) based P2Y12 antagonists.
Shanghai Hengrui Pharmaceutical
Design and synthesis of orally available MEK inhibitors with potent in vivo antitumor efficacy.
Takeda California
Structure-based design and synthesis of pyrrole derivatives as MEK inhibitors.
Takeda California
Discovery of TAK-733, a potent and selective MEK allosteric site inhibitor for the treatment of cancer.
Takeda California
Design, synthesis and SAR of RGD peptide hybrids as highly efficient inhibitors of platelet aggregation
TBA
Discovery of Highly Selective PARP7 Inhibitors with a Novel Scaffold for Cancer Immunotherapy.
China Pharmaceutical University
Carbohydrate Strengthens the Immunotherapeutic Effect of Small-Molecule PD-L1 Inhibitors.
Zhejiang University
Design, synthesis and biological evaluation of novel indole-piperazine derivatives as antibacterial agents.
Northwest A&F University
BRD4 inhibitor compound in solid form and preparation method therefor and use thereof
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)
2-amino-N-(arylsulfinyl)-acetamide compounds as inhibitors of bacterial aminoacyl-tRNA synthetase
Oxford Drug Design
ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE
Petra Pharma
JAK kinase inhibitor compounds for treatment of respiratory disease
Theravance Biopharma R&D Ip
Solid forms of a plasma kallikrein inhibitor and salts thereof
Kalvista Pharmaceuticals
1, 4, 6-trisubstituted-2-alkyl-1H-benzo[d]imidazole derivatives as dihydroorotate oxygenase inhibitors
Merck Patent
Methyl- and trifluromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof
Pfizer
Hydroxyindole carboxylic acid based inhibitors for oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2)
Indiana University Research and Technology
First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib.
University of Manchester
Synthesis and molecular modelling studies of novel sulphonamide derivatives as dengue virus 2 protease inhibitors.
Birla Institute of Technology
Enhanced ligand affinity for receptors in which components of the binding site are independently mobile.
University of Sheffield