BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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20 articles for SG Withers

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis of C-5a-chain extended derivatives of 4-epi-isofagomine: Powerfulß-galactosidase inhibitors and low concentration activators of GM1-gangliosidosis-related human lysosomalß-galactosidase.EBI
Graz University of Technology
Concise synthesis of C-1-cyano-iminosugars via a new Staudinger/aza Wittig/Strecker multicomponent reaction strategy.EBI
Technical University Graz
Rapid assembly of a library of lipophilic iminosugars via the thiol-ene reaction yields promising pharmacological chaperones for the treatment of Gaucher disease.EBI
University of British Columbia
Synthesis and biological evaluation of novel biotin-iminoalditol conjugates.EBI
Technische Universit£T Graz
N-Acetylhexosaminidase inhibitory properties of C-1 homologated GlcNAc- and GalNAc-thiazolines.EBI
The State University of New Jersey
Glycosidase profiling with immobilised glycosidase-inhibiting iminoalditols--a proof-of-concept study.EBI
Technische Universit£T Graz
A fluorescent probe for GM1 gangliosidosis relatedß-galactosidase: N-(dansylamino)hexylaminocarbonylpentyl-1,5-dideoxy-1,5-imino-D-galactitol.EBI
Industrial Research
OGA inhibition by GlcNAc-selenazoline.EBI
Daegu University
 
β-Glucosidase inhibitors incorporating pyridinium as a glucosyl mimicEBI
TBA
1-Deoxygalactonojirimycin-lysine hybrids as potent D-galactosidase inhibitors.EBI
Technische UniversitäT Graz
Fluorescent glycosidase inhibiting 1,5-dideoxy-1,5-iminoalditols.EBI
Technische UniversitäT Graz
Powerful probes for glycosidases: novel, fluorescently tagged glycosidase inhibitors.EBI
Institut FüR Biochemie Der Technischen UniversitäT Graz
Novel, lipophilic derivatives of 2,5-dideoxy-2,5-imino-D-mannitol (DMDP) are powerful beta-glucosidase inhibitors.EBI
Technische UniversitäT Graz
A new type of pharmacological chaperone for GEBI
Graz University of Technology
Substituted indazoles, methods for the production thereof, pharmaceutical preparations that contain said new substituted indazoles, and use of said new substituted indazoles to produce drugsBDB
Bayer Pharma Aktiengesellschaft
Kinase inhibitorsBDB
Topivert Pharma
Microwave-assisted synthesis and tyrosinase inhibitory activity of chalcone derivatives.BDB
Shaoyang University
Differences in agonist/antagonist binding affinity and receptor transduction using recombinant human gamma-aminobutyric acid type A receptors.BDB
Merck Sharp and Dohme Research Laboratories
Inhibition of adenosine deaminase by analogues of adenosine and inosine, incorporating a common heterocyclic base, 4(7)-amino-6(5)H-imidazo[4,5-d]pyridazin-7(4)one.BDB
University of Maryland Baltimore County