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14 articles for TG Davies


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery.EBI
Astex Pharmaceuticals
Identification of 4-(4-aminopiperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidines as selective inhibitors of protein kinase B through fragment elaboration.EBI
The Institute of Cancer Research
Discovery of 4-amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides as selective, orally active inhibitors of protein kinase B (Akt).EBI
The Institute of Cancer Research
Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2).EBI
Astex Pharmaceuticals
Fragment-Guided Discovery of Pyrazole Carboxylic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2 Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction.EBI
Astex Pharmaceuticals
Structure-Activity and Structure-Conformation Relationships of Aryl Propionic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1/Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1/NRF2) Protein-Protein Interaction.EBI
Astex Pharmaceuticals
Treatment of dry eyeBDB
Principia Biopharma
Diamide compounds having muscarinic receptor antagonist and β2 adrenergic receptor agonist activityBDB
Theravance Respiratory
Substituted 2-aminopyridine protein kinase inhibitorBDB
Chia Tai Tianqing Pharmaceutical Group
Heterocyclic compounds and methods for their useBDB
Novartis
4-(4-cyano-2-thioaryl)dihydropyrimidinones and use thereofBDB
Bayer Intellectual Property
Synthesis and SAR of potent EGFR/erbB2 dual inhibitors.BDB
Glaxosmithkline
Synthesis and initial SAR studies of 3,6-disubstituted pyrazolo[1,5-a]pyrimidines: a new class of KDR kinase inhibitors.BDB
Merck Research Laboratories