Binding Database

BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 760K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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8 articles for D Dalgarno

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Cmpds

Data

Article Title

Organization

51

Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase.

Ariad Pharmaceuticals

11

Application of MM-GB/SA and WaterMap to SRC Kinase Inhibitor Potency Prediction.

TBA

24

Novel N9-arenethenyl purines as potent dual Src/Abl tyrosine kinase inhibitors.

Ariad Pharmaceuticals

7

The Potent ALK Inhibitor Brigatinib (AP26113) Overcomes Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in Preclinical Models.

ARIAD Pharmaceuticals, Inc.

20

Investigating protein-ligand interactions with a mutant FKBP possessing a designed specificity pocket.

Ariad Gene Therapeutics

8

Pteridines as FGFR inhibitors

Astex Therapeutics

14

Piperidinone carboxamide azaindane CGRP receptor antagonists

Merck Sharp & Dohme

16

Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors.

Sunesis Pharmaceuticals